CTSS - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true nocite: | @barariaCathepsinAlterationsInduce2020,
Experimental Evidence
Driver mutations affecting this gene in FL have been experimentally demonstrated to cause a gain of function (GOF).[@dheillyCathepsinRegulatesAntigen2020]
Relevance tier by entity
Mutation incidence in large patient cohorts (GAMBL reanalysis)
DLBCL
FL
Mutation pattern and selective pressure estimates
CTSS Hotspots
| Chromosome | Coordinate (hg19) | ref>alt | HGVSp |
|---|---|---|---|
| chr1 | 150727482 | A>C | Y132D |
| chr1 | 150727482 | A>T | Y132N |
include:tables/browser_CTSS.md
Expression
include:tables/mermaid_CTSS.md