bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
Mutations in this gene were first described in DLBCL in 2021 by Hübschmann et al.1
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timeline
title Publication timing
2021-05-05 : Hübschmann : DLBCL
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Entity |
Tier |
Description |
|
2 |
relevance in DLBCL not firmly established[@hubschmannMutationalMechanismsShaping2021b] |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
Entity |
source |
frequency (%) |
DLBCL |
GAMBL genomes |
1.34 |
DLBCL |
Schmitz cohort |
0.64 |
DLBCL |
Reddy cohort |
1.20 |
DLBCL |
Chapuy cohort |
0.85 |
Mutation pattern and selective pressure estimates
Entity |
aSHM |
Significant selection |
dN/dS (missense) |
dN/dS (nonsense) |
BL |
No |
No |
1.053 |
0.000 |
DLBCL |
No |
No |
5.016 |
12.509 |
FL |
No |
No |
0.000 |
23.991 |
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
SP116690
SP59288
SP124984
SP116663
SP192997