CHD1 - morinlab/LLMPP GitHub Wiki
<<Warn("The variants reported in this gene in DLBCL failed QC")>>
Mutations in this gene were first described in DLBCL in 2017 by Reddy et al.1 Subsequent exome and genome-wide studies of DLBCL did not reproduce this observation.
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timeline
title Publication timing
2017-10-10 : Reddy : DLBCL
| Entity | Tier | Description |
|---|---|---|
 |
2 | relevance in DLBCL not firmly established[@reddyGeneticFunctionalDrivers2017] |
| Entity | source | frequency (%) |
|---|---|---|
| DLBCL | GAMBL genomes | 2.10 |
| DLBCL | Schmitz cohort | 2.98 |
| DLBCL | Reddy cohort | 2.90 |
| DLBCL | Chapuy cohort | 2.14 |
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | No | No | 0.674 | 2.751 |
| DLBCL | No | No | 1.993 | 4.965 |
| FL | No | No | 0.000 | 0.000 |
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
