CD44 - morinlab/LLMPP GitHub Wiki
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CD44
History
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timeline
title Publication timing
2018-10-01 : Arthur : DLBCL
Relevance tier by entity
Entity |
Tier |
Description |
|
2-a |
aSHM target; Although recurrent, the relevance of mutations in DLBCL is tenuous [@arthurGenomewideDiscoverySomatic2018] |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
Entity |
source |
frequency (%) |
DLBCL |
GAMBL genomes |
0.19 |
DLBCL |
Schmitz cohort |
1.49 |
DLBCL |
Reddy cohort |
1.40 |
DLBCL |
Chapuy cohort |
2.14 |
Mutation pattern and selective pressure estimates
Entity |
aSHM |
Significant selection |
dN/dS (missense) |
dN/dS (nonsense) |
BL |
Yes |
No |
0.00 |
0 |
DLBCL |
Yes |
No |
2.09 |
0 |
FL |
Yes |
No |
0.00 |
0 |
aSHM regions
chr_name |
hg19_start |
hg19_end |
region |
regulatory_comment |
chr11 |
35156769 |
35164248 |
TSS |
active_promoter |
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
CD44 Expression
References