CD22 - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true nocite: | @reddyGeneticFunctionalDrivers2017,
Overview
Mutations in this gene were first described in DLBCL in 2017 by Reddy et al.[@reddyGeneticFunctionalDrivers2017] Subsequent exome and genome-wide studies of DLBCL did not reproduce this observation.
Relevance tier by entity
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| DLBCL | GAMBL genomes | 1.15 |
| DLBCL | Schmitz cohort | 1.70 |
| DLBCL | Reddy cohort | 2.80 |
| DLBCL | Chapuy cohort | 2.99 |
Mutation pattern and selective pressure estimates
include:tables/browser_CD22.md
Expression
include:tables/mermaid_CD22.md