CD22 - morinlab/LLMPP GitHub Wiki
Mutations in this gene were first described in DLBCL in 2017 by Reddy et al.1 Subsequent exome and genome-wide studies of DLBCL did not reproduce this observation.
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timeline
title Publication timing
2017-10-10 : Reddy : DLBCL
Entity | Tier | Description |
---|---|---|
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2 | relevance in DLBCL not firmly established[@reddyGeneticFunctionalDrivers2017] |
Entity | source | frequency (%) |
---|---|---|
DLBCL | GAMBL genomes | 1.15 |
DLBCL | Schmitz cohort | 1.70 |
DLBCL | Reddy cohort | 2.80 |
DLBCL | Chapuy cohort | 2.99 |
Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
---|---|---|---|---|
BL | No | No | 4.287 | 0 |
DLBCL | No | No | 1.951 | 0 |
FL | No | No | 0.000 | 0 |
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38