CBLB - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true nocite: | @reddyGeneticFunctionalDrivers2017,
Overview
Mutations in this gene were first described in DLBCL in 2017 by Reddy et al.[@reddyGeneticFunctionalDrivers2017] Subsequent exome and genome-wide studies of DLBCL did not reproduce this observation.
Relevance tier by entity
Warnings
<<Warn("The variants reported in this gene in DLBCL failed QC")>>
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| DLBCL | GAMBL genomes | 1.72 |
| DLBCL | Schmitz cohort | 2.77 |
| DLBCL | Reddy cohort | 1.60 |
| DLBCL | Chapuy cohort | 1.71 |
Mutation pattern and selective pressure estimates
include:tables/browser_CBLB.md
Expression
All Mutations
Reddy_2084T Reddy_2088T Reddy_2107T Reddy_2163T Reddy_2208T Reddy_2222T Reddy_2270T Reddy_2291T Reddy_2293T Reddy_2448T Reddy_2471T Reddy_2643T Reddy_2720T Reddy_2805T Reddy_2832T Reddy_2919T Reddy_2948T Reddy_2953T Reddy_2996T Reddy_3386T Reddy_3433T Reddy_3622T Reddy_3628T Reddy_3697T Reddy_3732T Reddy_3837T Reddy_3845T Reddy_3846T Reddy_3942T Reddy_3959T Reddy_3971T Reddy_3999T Reddy_4000T
include:tables/mermaid_CBLB.md