CADPS2 - morinlab/LLMPP GitHub Wiki

bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

CADPS2

History

Mutations in this gene were first described in DLBCL in 2021 by Hübschmann et al.1

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timeline
    title Publication timing
      2021-05-05 : Hübschmann : DLBCL
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Relevance tier by entity

Entity Tier Description
DLBCL 2 relevance in DLBCL not firmly established[@hubschmannMutationalMechanismsShaping2021b]

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
DLBCL GAMBL genomes 3.63
DLBCL Schmitz cohort 6.38
DLBCL Reddy cohort 4.30
DLBCL Chapuy cohort 1.71

Mutation pattern and selective pressure estimates

Entity aSHM Significant selection dN/dS (missense) dN/dS (nonsense)
BL No No 0.311 2.676
DLBCL No No 1.217 1.199
FL No No 0.921 0.000

View coding variants in ProteinPaint hg19 or hg38

View all variants in GenomePaint hg19 or hg38

CADPS2 Expression

All Mutations

SP116697 SP116690 SP116668 SP59460 SP59372 SP192997 SP124971 SP192970

References

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