BMP7 - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true
BMP7
History
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timeline
title Publication timing
2019-09-26 : Panea : BL
Relevance tier by entity
| Entity | Tier | Description |
|---|---|---|
 |
1 | high-confidence BL gene[@paneaWholeGenomeLandscape2019] |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| BL | GAMBL genomes+capture | 6.47 |
| BL | Thomas cohort | 8.90 |
| BL | Panea cohort | 5.00 |
Mutation pattern and selective pressure estimates
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | No | Yes | 5.863 | 16.044 |
| DLBCL | No | No | 6.236 | 10.787 |
| FL | No | No | 1.371 | 0.000 |
BMP7 Hotspots
| Chromosome | Coordinate (hg19) | ref>alt | HGVSp |
|---|---|---|---|
| chr20 | 55841157 | C>T | A8T |
| chr20 | 55841157 | C>G | A8P |
| chr20 | 55841156 | G>C | A8G |
| chr20 | 55841155 | AG>TA | A8V |
| chr20 | 55840966 | G>T | H71Q |
| chr20 | 55840965 | G>C | L72V |
| chr20 | 55840962 | G>C | Q73E |
| chr20 | 55840958 | C>T | G74D |
| chr20 | 55840954 | C>A | K75N |
| chr20 | 55840953 | G>T | H76N |
| chr20 | 55840953 | G>C | H76D |
| chr20 | 55840953 | G>A | H76Y |
| chr20 | 55840944 | C>G | A79P |
| chr20 | 55840935 | A>G | F82L |
| chr20 | 55840918 | G>C | Y87* |
| chr20 | 55840913 | G>T | A89D |
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
BMP7 Expression
