BMP7 - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
BMP7
History
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timeline
title Publication timing
2019-09-26 : Panea : BL
Relevance tier by entity
Entity |
Tier |
Description |
![BL](https://github.com/morinlab/LLMPP/wiki/images/icons/BL_tier1.png) |
1 |
high-confidence BL gene[@paneaWholeGenomeLandscape2019] |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
Entity |
source |
frequency (%) |
BL |
GAMBL genomes+capture |
6.47 |
BL |
Thomas cohort |
8.90 |
BL |
Panea cohort |
5.00 |
Mutation pattern and selective pressure estimates
Entity |
aSHM |
Significant selection |
dN/dS (missense) |
dN/dS (nonsense) |
BL |
No |
Yes |
5.863 |
16.044 |
DLBCL |
No |
No |
6.236 |
10.787 |
FL |
No |
No |
1.371 |
0.000 |
BMP7 Hotspots
Chromosome |
Coordinate (hg19) |
ref>alt |
HGVSp |
chr20 |
55841157 |
C>T |
A8T |
chr20 |
55841157 |
C>G |
A8P |
chr20 |
55841156 |
G>C |
A8G |
chr20 |
55841155 |
AG>TA |
A8V |
chr20 |
55840966 |
G>T |
H71Q |
chr20 |
55840965 |
G>C |
L72V |
chr20 |
55840962 |
G>C |
Q73E |
chr20 |
55840958 |
C>T |
G74D |
chr20 |
55840954 |
C>A |
K75N |
chr20 |
55840953 |
G>T |
H76N |
chr20 |
55840953 |
G>C |
H76D |
chr20 |
55840953 |
G>A |
H76Y |
chr20 |
55840944 |
C>G |
A79P |
chr20 |
55840935 |
A>G |
F82L |
chr20 |
55840918 |
G>C |
Y87* |
chr20 |
55840913 |
G>T |
A89D |
View coding variants in ProteinPaint hg19 or hg38
![](https://github.com/morinlab/LLMPP/wiki/images/proteinpaint/BMP7_NM_001719.svg)
View all variants in GenomePaint hg19 or hg38
![](https://github.com/morinlab/LLMPP/wiki/images/proteinpaint/BMP7.svg)
BMP7 Expression
![](https://github.com/morinlab/LLMPP/wiki/images/gene_expression/BMP7_by_pathology.svg)
References