BACH2 - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true nocite: | @grandeGenomewideDiscoverySomatic2019,
Overview
Mutations in this gene were first described in BL in 2019 by Grande et al.[@grandeGenomewideDiscoverySomatic2019]
Experimental Evidence
Driver mutations affecting this gene in BL have been experimentally demonstrated to cause a reduction or loss of function (LOF).[@hunterNFkBSubunitCRel2016]
Relevance tier by entity
Mutation incidence in large patient cohorts (GAMBL reanalysis)
BL
Mutation pattern and selective pressure estimates
aSHM regions
| chr_name | hg19_start | hg19_end | region | regulatory_comment |
|---|---|---|---|---|
| chr6 | 90981034 | 91016134 | TSS | NA |
include:tables/browser_BACH2.md
Expression
include:tables/mermaid_BACH2.md