ATR - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true nocite: | @reddyGeneticFunctionalDrivers2017,
Overview
Mutations in this gene were first described in DLBCL in 2017 by Reddy et al.[@reddyGeneticFunctionalDrivers2017] Subsequent exome and genome-wide studies of DLBCL did not reproduce this observation.
Relevance tier by entity
Mutation incidence in large patient cohorts (GAMBL reanalysis)
| Entity | source | frequency (%) |
|---|---|---|
| DLBCL | GAMBL genomes | 2.68 |
| DLBCL | Schmitz cohort | 4.89 |
| DLBCL | Reddy cohort | 2.80 |
| DLBCL | Chapuy cohort | 3.85 |
Mutation pattern and selective pressure estimates
Expression
Representative Mutations
Rating
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Rating
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All Mutations
Reddy_2121T Reddy_2150T Reddy_2163T Reddy_2192T Reddy_2195T Reddy_2206T Reddy_2236T Reddy_2475T Reddy_2476T Reddy_2585T Reddy_2594T Reddy_2758T Reddy_2768T Reddy_2775T Reddy_2779T Reddy_2805T Reddy_2828T Reddy_2838T Reddy_2898T Reddy_2933T Reddy_2947T Reddy_3384T Reddy_3385T Reddy_3405T Reddy_3489T Reddy_3502T Reddy_3520T Reddy_3548T Reddy_3549T Reddy_3557T Reddy_3561T Reddy_3562T Reddy_3594T Reddy_3622T Reddy_3653T Reddy_3662T Reddy_3779T Reddy_3810T Reddy_3812T Reddy_3820T Reddy_3822T Reddy_3843T Reddy_3856T Reddy_3879T Reddy_3992T Reddy_705T