---

bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

ARID1B

<<Warn("The variants reported in this gene in DLBCL failed QC")>>

History

%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
timeline
    title Publication timing
      2017-10-10 : Reddy : DLBCL

Relevance tier by entity

Entity	Tier	Description
	3	Retired, Failed QC[@reddyGeneticFunctionalDrivers2017]
	2	relevance in MCL not firmly established

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity	source	frequency (%)
DLBCL	GAMBL genomes	5.16
DLBCL	Schmitz cohort	5.96
DLBCL	Reddy cohort	3.30
DLBCL	Chapuy cohort	2.14
MCL	GAMBL genomes	1.90

Mutation pattern and selective pressure estimates

Entity	aSHM	Significant selection	dN/dS (missense)	dN/dS (nonsense)
BL	No	No	0.659	4.236
DLBCL	No	No	0.969	13.782
FL	No	No	0.747	11.009

View coding variants in ProteinPaint hg19 or hg38

View all variants in GenomePaint hg19 or hg38

ARID1B Expression

All Mutations

Reddy_2072T Reddy_2076T Reddy_2142T Reddy_2163T Reddy_2217T Reddy_2219T Reddy_2220T Reddy_2228T Reddy_2261T Reddy_2262T Reddy_2298T Reddy_2303T Reddy_2461T Reddy_2464T Reddy_2479T Reddy_2539T Reddy_2562T Reddy_2567T Reddy_2581T Reddy_2624T Reddy_2626T Reddy_2639T Reddy_2643T Reddy_2706T Reddy_2773T Reddy_2775T Reddy_2785T Reddy_3401T Reddy_3412T Reddy_3438T Reddy_3462T Reddy_3467T Reddy_3486T Reddy_3495T Reddy_3496T Reddy_3504T Reddy_3505T Reddy_3528T Reddy_3560T Reddy_3596T Reddy_3609T Reddy_3610T Reddy_3616T Reddy_3638T Reddy_3640T Reddy_3644T Reddy_3647T Reddy_3652T Reddy_3655T Reddy_3660T Reddy_3663T Reddy_3679T Reddy_3686T Reddy_3687T Reddy_3707T Reddy_3708T Reddy_3715T Reddy_3725T Reddy_3726T Reddy_3732T Reddy_3740T Reddy_3764T Reddy_3811T Reddy_3832T Reddy_3886T Reddy_3898T Reddy_3921T Reddy_3923T Reddy_3935T Reddy_3939T Reddy_3941T Reddy_3944T Reddy_3967T Reddy_3979T Reddy_3980T Reddy_3986T Reddy_816T Reddy_823T

References