ANKRD12 - morinlab/LLMPP GitHub Wiki

bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

ANKRD12

History

Mutations in this gene were first described in DLBCL in 2021 by Hübschmann et al.1

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    title Publication timing
      2021-05-05 : Hübschmann : DLBCL
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Relevance tier by entity

Entity Tier Description
DLBCL 2 relevance in DLBCL not firmly established[@hubschmannMutationalMechanismsShaping2021b]

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
DLBCL GAMBL genomes 2.29
DLBCL Schmitz cohort 6.17
DLBCL Reddy cohort 2.10
DLBCL Chapuy cohort 5.13

Mutation pattern and selective pressure estimates

Entity aSHM Significant selection dN/dS (missense) dN/dS (nonsense)
BL No No 1.649 0.000
DLBCL No No 0.885 4.832
FL No No 0.000 0.000

View coding variants in ProteinPaint hg19 or hg38

View all variants in GenomePaint hg19 or hg38

ANKRD12 Expression

All Mutations[@hubschmannMutationalMechanismsShaping2021b]

SP193744 SP116697 SP116726 SP193467 SP193681 SP194035 SP193375

References

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