AICDA - morinlab/LLMPP GitHub Wiki
bibliography: 'morinlab.bib'
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AICDA
History
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timeline
title Publication timing
2018-10-01 : Arthur : DLBCL
Relevance tier by entity
Entity |
Tier |
Description |
|
2-a |
aSHM target; Although recurrent, the relevance of mutations in DLBCL is tenuous [@arthurGenomewideDiscoverySomatic2018] |
Mutation incidence in large patient cohorts (GAMBL reanalysis)
Entity |
source |
frequency (%) |
DLBCL |
GAMBL genomes |
0.38 |
DLBCL |
Schmitz cohort |
0.43 |
DLBCL |
Reddy cohort |
0.30 |
DLBCL |
Chapuy cohort |
0.43 |
Mutation pattern and selective pressure estimates
Entity |
aSHM |
Significant selection |
dN/dS (missense) |
dN/dS (nonsense) |
BL |
Yes |
No |
2.589 |
0 |
DLBCL |
Yes |
No |
2.652 |
0 |
FL |
Yes |
No |
4.955 |
0 |
aSHM regions
chr_name |
hg19_start |
hg19_end |
region |
regulatory_comment |
chr12 |
8762328 |
8765099 |
TSS |
NA |
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
AICDA Expression
References