ABI3BP - morinlab/LLMPP GitHub Wiki

bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

ABI3BP

History

Mutations were first described in DLBCL in 2013 by Morin et al.1 Subsequent exome and genome-wide studies of DLBCL did not reproduce this observation.

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timeline
    title Publication timing
      2013-08-15 : Morin : DLBCL
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Relevance tier by entity

Entity Tier Description
DLBCL 2 relevance in DLBCL not firmly established[@morinMutationalStructuralAnalysis2013]

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
DLBCL GAMBL genomes 3.44
DLBCL Schmitz cohort 2.34
DLBCL Reddy cohort 1.80
DLBCL Chapuy cohort 2.99

Mutation pattern and selective pressure estimates

Entity aSHM Significant selection dN/dS (missense) dN/dS (nonsense)
BL No No 2.366 2.365
DLBCL No No 1.625 0.000
FL No No 2.009 0.000

View coding variants in ProteinPaint hg19 or hg38

View all variants in GenomePaint hg19 or hg38

ABI3BP Expression

All Mutations

RG014 RG054 RG067 RG081

References

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