Peptide Properties of Saccharomyces arboricola H 6 Suggest Randomness in Chromosomal Organization - mauriceling/mauriceling.github.io GitHub Wiki

Citation: Roh, D, Naing, SY, Ling, MHT. 2023. Peptide Properties of Saccharomyces arboricola H-6 Suggest Randomness in Chromosomal Organization. EC Microbiology 19(3): 01-08.

Link to [abstract].

Here is the permanent [PDF], and [Data Set] links to my archive.

Eukaryotic genomes are organized into multiple chromosomes and studies have suggested that chromosomal organization is subjected to evolutionary pressure as demonstrated by non-randomness of properties across chromosomes. However, a recent study provided evidence to suggest that chromosomal organization may be more random in unicellular than multicellular eukaryotes. Here, we examine the distribution of five peptide features (length, aromaticity, instability, hydropathy, and isoelectric point) across the 16 nuclear chromosomes of Saccharomyces arboricola H-6, a recently identified and sequenced unicellular eukaryote. Our results show that only hydropathy is not random across the chromosomes (F = 1.914, p-value = 0.018); thereby, supporting the hypothesis that chromosomal organization may be random in unicellular eukaryotes.