Welcome to the MrBiomics wiki!

Here you find:

• Detailed instructions, including code snippets, on how to use individual MrBiomics Modules.
• A tutorial on how to use modules within your Snakemake workflows or projects.
• Module specifications that ensure compatibility, reproducibility, and sustainability.
• Recipes for the most conceivable standard analyses, including tutorials, e.g., for comprehensive RNA-seq Analysis.

[!TIP] Use the sidebar for easier navigation.

Click to view the latest project slide deck.

🌟 Motivation

Three (subjective) key observations at the end of 2021 motivated me to start this project.

• Increased demand, but limited resources.
  • The balance between data generators and data analysts is getting worse and communication suffers.
  • There is no sustainable framework to preserve complex inventions and best practices.
  • Established innovation methods (e.g., design thinking, fast prototyping, agile concepts,...) can not be leveraged.
• An increasing number of fields of relevance and interest, but not more time.
  • Staying current in one field is getting harder.
  • Getting into novel fields takes time and is risky.
  • Method development is very competitive and takes a lot of time, hence it requires determination and focus.
• Reproducibility crisis and recent technological developments.
  • Established analyses/approaches are often “reinvented”, leading to irreproducible results.
  • Recent developments in workflow management enable a mindset shift towards software engineering best practices.
  • Compounding effects of re-using established best practices become possible.