Domains - OHDSI/Vocabulary-v5.0 GitHub Wiki
Domains are OMOP-defined clinical entity categories that are defined for each Concept in the Standardized Vocabulary. A list of all Domains is stored in the DOMAIN table. In the CONCEPT table, the field domain_id of each Concept record determines the Domain the Concept belongs to.
All Standard and Classification Concepts (standard_concept = 'S' or 'C') have a unique Domain, while the non-standard Source Concepts (standard_concept = NULL) can have domain_id entries that represent combinations of domains.
Domain assignments are done using a heuristic, which is different for each vocabulary. Most vocabularies have Concepts in one of few Domains, but some of them, like HCPCS or Read, are very broad. The assignment will follow the following logic:
| Domain | Definition | CDM Table |
|---|---|---|
| Condition | Represents concepts indicating clinical states observed, diagnosed, or reported for a patient, including diseases, disorders, signs, and symptoms. Conditions describe an assertion about health status, not a performed action or a measured result. Typically derived from problem lists, diagnosis billing codes, or clinical documentation. | CONDITION_OCCURRENCE and CONDITION_ERA |
| Drug | Covers terms representing chemical or biological substances formulated to exert a therapeutic effect when introduced into the body. Encompasses drug products, active ingredients, delivery forms (e.g., oral tablets, injections, topical creams), vaccines, and combination products. Unlike Devices, which act through physical means, Drugs primarily act through chemical or biological mechanisms. | DRUG_EXPOSURE and DRUG_ERA |
| Procedure | Defines activities or interventions (actions) ordered by or performed by healthcare providers for diagnostic, therapeutic, or preventive purposes. Examples include surgeries, imaging studies, biopsies, and catheterizations. Compared to Measurements, Procedures record the act of performing an activity (e.g., 4307315 "Gram stain microscopy" [performed, with no result recorded]), while Measurements capture the result or findings from that activity (e.g., "Gram stain microscopy" [with result, such as detection of Gram-positive cocci]). Compared to Devices, Procedures involve clinical activities, whereas Devices represent tangible instruments used. For example, "Oxygen administration by non-rebreather mask" is a Procedure, while "Non-rebreather oxygen mask" is a Device. | PROCEDURE _ OCCURRENCE |
| Measurement | Represents terms related to structured, standardized evaluations or tests performed on a person or their specimen, yielding numeric, categorical, or ordinal results. Includes laboratory tests/procedures, vital signs, pathology reports with quantitative findings, assessment instruments such as staging, scales, and scores (but not all of them), observable entities with information about a quality or property to be observed (but not all of them), some clinical findings with qualitative results of testing. Measurements differ from Procedures in that they capture the measured result, not the act of measurement itself. Measurements differ from Observations in that they are structured, objective outputs of standardized assessments, often with units or standardized categories. | MEASUREMENT |
| Observation | Encompasses clinical facts, findings, or statements about a patient that are not covered by other domains. Includes medical and family history, social determinants of health, patient-reported outcomes, lifestyle factors (e.g., smoking status), or subjective assessments (e.g., patient feels well). Observations are often qualitative, subjective, or context-driven and may or may not arise from a formal test. They differ from Conditions, which represent defined diseases or pathological states requiring diagnosis, and from Measurements, which represent standardized numeric or categorical results obtained through structured testing. | OBSERVATION |
| Device | Covers terms representing physical objects or instruments used in patient care for diagnostic, therapeutic, or assistive purposes, acting by mechanical, structural, or material means rather than chemical action. Includes implantable devices (e.g. pacemakers, stents, artificial joints), external devices (e.g., wheelchairs, oxygen masks), instruments used in medical procedures (e.g. defibrillators), material used in clinical care (e.g. adhesives, body material, dental material, surgical material), monitoring devices (e.g., infusion pumps), prosthetics, assistive technologies, contrast agents, food supplements, and infant formula. Devices differ from Drugs in that they do not exert their primary intended effect through chemical action. Devices differ from Procedures, which describe the clinical use or placement of a device rather than the device itself. | DEVICE_EXPOSURE |
| Specimen | Represents concepts describing biological samples collected from a person for laboratory testing, clinical diagnostics, biobanking, or research purposes. Specimen concepts standardize the nature of the sample (e.g., "Blood specimen", "Tumor tissue specimen", "Saliva sample") and are used to classify biological material consistently within the OMOP Vocabulary. | SPECIMEN |
| Visit | Defines the context of healthcare encounters, grouping clinical activities by encounter type. Includes outpatient visits, emergency department encounters, inpatient stays, and more granular units (ICU or observation room). Visits provide a temporal and contextual framework for interpreting other events (Conditions, Procedures, Measurements). | VISIT_OCCURRENCE and VISIT_DETAIL |
| Provider | Represents concepts describing individual human healthcare professionals involved in the delivery of patient care. This includes physicians, nurses, pharmacists, therapists, and other clinical practitioners. Provider concepts capture the role or type of healthcare professional, distinct from Care Site concepts, which represent institutions, facilities, or organizational locations where care is provided. | PROVIDER |
However, for some of the categories, the assignment can be ambiguous. For these cases, in the OMOP Standardized Vocabulary we use the following rules:
| Category | Example | Domain |
| Behavioral abnormality | ICD10CM Z72.810 Child and adolescent antisocial behavior | Condition |
| Blood bank product | CPT4 86930 Frozen blood, each unit; freezing (includes preparation) | Device |
| Contrast material for imaging | HCPCS A9581 Injection, gadoxetate disodium, 1 ml | Device |
| Food Supplement | SPL 304fdee6-0290-4717-be3d-b367bec7e411 Ferrous Gluconate | Device |
| Graft (alive or artificial) | HCPCS L8670 Vascular graft material, synthetic, implant | Device |
| Implant (not drug eluding) | HCPCS L8610 Ocular implant | Device |
| Medical supply | HCPCS A4336 Incontinence supply, urethral insert, any type, each | Device |
| Nutrition (enteral) | HCPCS B4152 Enteral formula, nutritionally complete, calorically dense (equal to or greater than 1.5 kcal/ml) with intact nutrients, includes proteins, fats, carbohydrates, vitamins and minerals, may include fiber, administered through an enteral feeding tube, 100 cal… | Device |
| Nutrition (parenteral) | HCPCS B5200 Parenteral nutrition solution: compounded amino acid and carbohydrates with electrolytes, trace elements, and vitamins, including preparation, any strength, stress - branch chain amino acids - premix | Device |
| Prosthesis | HCPCS L6687 Upper extremity addition, frame type socket, below elbow or wrist disarticulation | Device |
| Radioactive material for imaging | HCPCS C1204 Technetium tc 99m tilmanocept, diagnostic, up to 0.5 millicuries | Device |
| Radiological procedure supply, radiopharmaceutical) | HCPCS C2644 Brachytherapy source, cesium-131 chloride solution, per millicurie | Device |
| Animal Drug | SPL 3cc46410-1360-43ba-af4f-fd33c9bc3533 THYROID SOOTHE - chamomilla, iodium, lycopus, nux vom, zingiber spray | Drug |
| Cellular Therapy | RxNorm 1000596 autologous cultured chondrocytes 30000000 CELLS/ML Injectable Solution [Carticel] | Drug |
| Implant (drug eluding) | HCPCS J7311 Fluocinolone acetonide, intravitreal implant | Drug |
| Procedure Drug | HCPSC J2704 Injection, propofol, 10 mg | Drug |
| Cytogenetic study | CPT4 88271 Molecular cytogenetics; DNA probe, each (eg, FISH) | Measurement |
| Cytopathology | CPT4 1012386 Cytopathology smears, cervical or vaginal | Measurement |
| Drug testing | HCPCS G6030 Amitriptyline (Assay of amitriptyline) | Measurement |
| Electrocardiogram | HCPCS G0403 Electrocardiogram, routine ecg with 12 leads; performed as a screening for the initial preventive physical examination with interpretation and report | Measurement |
| Hearing test | CPT4 92563 Hearing test using earphones | Measurement |
| Immunological test procedure | CPT4 95065 Direct nasal mucous membrane test | Measurement |
| Semen analysis | HCPCS G0027 Semen analysis; presence and/or motility of sperm excluding huhner | Measurement |
| Cosmetic | SPL 8491b3d2-1edc-4694-adf7-b9649edb00eb ONWARD CHAPSTICK - lipstick | Observation |
| Evaluation or assessment | HCPCS G8930 Assessment of depression severity at the initial evaluation | Observation |
| Lifestyle choice | ICD10 Z58.7 Exposure to tobacco smoke | Observation |
| Pathology report | HCPCS G9428 Pathology report includes the pt category and a statement on thickness and ulceration and for pt1, mitotic raten | Observation |
| Service without exact procedure | HCPCS H0030 Behavioral health hotline service, HCPCS H2016 Comprehensive community support services, per diem | Observation |
| Visit without procedure | HCPCS S9127 Social work visit, in the home, per diem | Observation |
| Anything called *ectomy | HCPCS S2350 Diskectomy, anterior, with decompression of spinal cord and/or nerve root(s), including osteophytectomy; lumbar, single interspace except some devices having *ectomy in description like HCPCS L8020 Breast prosthesis, mastectomy form | Procedure |
| Anything called *graphy | HCPCS C9733 Non-ophthalmic fluorescent vascular angiography | Procedure |
| Anything called *scopy | HCPCS S2070 Cystourethroscopy, with ureteroscopy and/or pyeloscopy; with endoscopic laser treatment of ureteral calculi (includes ureteral catheterization) | Procedure |
| Attention | ICD10 Z43.5 Attention to Cyctostomy | Procedure |
| Brachytherapy | HCPCS G0458 Low dose rate (ldr) prostate brachytherapy services, composite rate | Procedure |
| Counseling | HCPCS H0005 Alcohol and/or drug services; group counseling by a clinician | Procedure |
| Detoxification | HCPCS H0009 Alcohol and/or drug services; acute detoxification (hospital inpatient) | Procedure |
| Examination | ICD10 Z01.0 Examination of eyes and vision | Procedure |
| Imaging | CPT4 91110 Gastrointestinal tract imaging, intraluminal (eg, capsule endoscopy), esophagus through ileum, with interpretation and report | Procedure |
| Immunotherapy | CPT4 95115 Professional services for allergen immunotherapy not including the provision of allergenic extracts; single injection | Procedure |
| Management | ICD10 Z30.9 Contraceptive management, unspecified | Procedure |
| Monitoring | HCPCS 59050 Fetal monitoring during labor by consulting physician (ie, non-attending physician) with written report; supervision and interpretation | Procedure |
| Physician consult | CPT4 1014276 Pathology consultation during surgery | Procedure |
| Procedure Drug (without exact drug information and no RxNorm mapping) | HCPCS J8498 Antiemetic drug, rectal/suppository, not otherwise specified | Procedure |
| Service with exact procedure | HCPCS H0005 Alcohol and/or drug services; group counseling by a clinician | Procedure |
| Surgical pathology (gross or microscopic) | CPT4 88300 Level I - Surgical pathology, gross examination only | Procedure |
| Visit with exact procedure | HCPCS S9097 Home visit for wound care | Procedure |
- Condition
- Currency
- Device
- Drug
- Ethnicity
- Gender
- Measurement
- Measurement Value
- Measurement Value Operator
- Metadata
- Modifier
- Observation
- Place of Service
- Procedure
- Provider Specialty
- Race
- Relationship
- Revenue Code
- Route of Administration
- Specimen
- Specimen Anatomic Site
- Specimen Disease Status
- Type Concept
- Unit
- Visit
- Combination Domains