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What does Synthesis do?
It allows modders to develop mods via code rather than by hand. These are often referred to as "patchers".
As a user creating a modded load order, Synthesis lets you add as many of these patcher mods as you like, and bundle them together into one single mod file: Synthesis.esp. You should rerun the Synthesis pipeline any time you add/remove mods so the patchers can change and adapt to the new content.
For Users:
Easily add patchers and run patcher pipelines on your game.
For Developers:
Typically, you want to utilize development tools provided by Synthesis to help you create Mutagen patchers from scratch.