Output File Column Descriptions - McIntyre-Lab/TranD GitHub Wiki

Table of Contents

1 GTF Gene Mode - Event ER Output File

Column Name Description
gene_id Gene ID
transcript_id Piped ("|") list of transcript IDs the exon region is present in
ER_id Exon region ID (continuous region of exonic space present in either any transcript)
ER_chr Chromosome exon region is located
ER_start Start coordinate of exon region (0-based)
ER_end End coordinate of exon region
ER_strand Strand of exon region
exons_per_ER Number of exons in exonic region
exon_id Piped ("|") list of exon IDs that are contained within the exon region
transcripts_per_ER Number of transcripts assoicated with the exon region
annotation_frequency Annotation frequency as either “unique”, “common”, “constitutive”
flag_ER_IR Binary indicator (1,0) if the exon region contains an intron retention event (where an intron of one transcript is entirely contained within an exon of the other transcript)

1 GTF Gene Mode - Event EF Output File

Column Name Description
gene_id Gene ID
transcript_id Piped ("|") list of transcript IDs the EF is present in
EF_id EF ID (distinct exon EF present in any transcript in the gene), formatted as [associated exon region ID]:[EF number within exon region]
EF_chr Chromosome EF is located
EF_start Start coordinate of EF (0-based)
EF_end End coordinate of EF
EF_strand Strand of EF
ER_id Exon region ID  the EF is contained within (continuous region of exonic space present in either any transcript)
ER_chr Chromosome exon region is located
ER_start Start coordinate of exon region (0-based)
ER_end End coordinate of exon region
ER_strand Strand of exon region
exon_id Piped ("|") list of exon IDs that are contained within the EF
exons_per_EF Number of exons in EF
transcripts_per_EF Number of transcripts assoicated with the EF
annotation_frequency Annotation frequency as either “unique”, “common”, “constitutive”
flag_EF_IR Binary indicator (1,0) if the EF is involved in an intron retention event (where an intron of one transcript is entirely contained within an exon of the other transcript)

1 GTF Pairwise Mode - Event Output File

Column Name Description
gene_id Gene ID
transcript_1 Transcript ID for transcript 1
transcript_2 Transcript ID for transcript 2
transcript_id Piped ("|") list of transcript IDs the EF is present in (if only in transcript 1 then transcript_id = transcript_1, if only in transcript 2 then transcript_id = transcript_2, if present in both then transcript_id = transcript_1|transcript_2)
EF_id EF ID (distinct exon EF present in either transcript 1 or transcript 2)
EF_chr Chromosome EF is located
EF_start Start coordinate of EF (0-based)
EF_end End coordinate of EF
EF_strand Strand of EF
ER_id Exon region ID  the EF is contained within (continuous region of exonic space present in either transcript 1 or transcript 2)
ER_chr Chromosome exon region is located
ER_start Start coordinate of exon region (0-based)
ER_end End coordinate of exon region
ER_strand Strand of exon region
flag_EF_IR Binary indicator (1,0) if the EF is involved in an intron retention event (where an intron of one transcript is entirely contained within an exon of the other transcript)

1 GTF Pairwise Mode - Pairwise Distance Output File

Column Name Description
gene_id Gene ID
transcript_1 Transcript ID for transcript 1 (T1)
transcript_2 Transcript ID for transcript 2 (T2)
num_jxn_only_T1 Number of junctions in transcript 1 only
num_jxn_only_T2 Number of junctions in transcript 2 only
num_jxn_same Number of junctions same in transcript 1 and transcript 2
prop_jxn_same Proportion of shared junctions (num_jxn_same/(num_jxn_only_T1 + num_jxn_only_T2 + num_jxn_same))
prop_jxn_notSame 1 - prop_jxn_same
jxn_string_T1 Piped ("|") list of all junction IDs (chr:start:end:strand) in transcript 1
jxn_string_T2 Piped ("|") list of all junction IDs (chr:start:end:strand) in transcript 2
jxn_only_T1 Piped ("|") list of junction IDs (chr:start:end:strand) in transcript 1 only
jxn_only_T2 Piped ("|") list of junction IDs (chr:start:end:strand) in transcript 2 only
jxn_same Piped ("|") list of junction IDs (chr:start:end:strand) same in transcript 1 and transcript 2
num_ER_only_T1 Number of exon regions in transcript 1 only
num_ER_only_T2 Number of exon regions in transcript 2 only
num_ER_ovlp Number of exon regions overlapping by transcript 1 and transcript 2
prop_ER_ovlp Proportion of overlapping exon regions (num_ER_ovlp/(num_ER_only_T1 + num_ER_only_T2 + num_ER_ovlp))
prop_ER_noOvlp 1 - prop_ER_ovlp
ER_only_T1 Piped ("|") list of exon region IDs in transcript 1 only
ER_only_T2 Piped ("|") list of exon region IDs in transcript 2 only
ER_ovlp Piped ("|") list of exon region IDs overlapping by transcript 1 and transcript 2
num_EF_only_T1 Number of exon EFs in transcript 1 only
num_EF_only_T2 Number of exon EFs in transcript 2 only
num_EF_ovlp Number of exon EFs overlapping by transcript 1 and transcript 2
prop_EF_ovlp Proportion of overlapping exon EFs (num_EF_ovlp/(num_EF_onlyt_T1 + num_EF_only_T2 + num_EF_ovlp))
prop_EF_noOvlp 1 - prop_EF_ovlp
EF_only_T1 Piped ("|") list of exon EF IDs in transcript 1 only
EF_only_T2 Piped ("|") list of exon EF IDs in transcript 2 only
EF_ovlp Piped ("|") list of exon EF IDs shared by transcript 1 and transcript 2
num_exon_only_T1 Number of full exons in transcript 1 only
num_exon_only_T2 Number of full exons in transcript 2 only
num_exon_ovlp Number of full exons overlapping  by transcript 1 and transcript 2
num_IR_EF_T1 Number of intron retention events in transcript 1 (where an intron of transcript 2 is entirely contained within an exon of transcript 2)
num_IR_EF_T2 Number of intron retention events in transcript 2 (where an intron of transcript 1 is entirely contained within an exon of transcript 2)
IR_EF_T1 Piped ("|") list of intron IDs (chr:start:end:strand) retained in transcript 1
IR_EF_T2 Piped ("|") list of intron IDs (chr:start:end:strand) retained in transcript 2
num_nt_ovlp Number of nucleotides overlapping in transcript 1 and transcript 2
num_nt_only_T1 Number of nucleotides in transcript 1 only
num_nt_only_T2 Number of nucleotides in transcript 2 only
num_nt_noOvlp Number of nucleotides exclusive to transcript 1 or transcript 2
total_nt Total number of nucleotides covered by either transcript 1 or transcript 2 (union)
prop_nt_noOvlp Proportion of different nucleotides ((num_nt_only_T1 + num_nt_only_T2)/total_nt)
prop_nt_ovlp Proportion of shared nucleotides (num_nt_ovlp/total_nt)
num_nt_only_T1_in_ovlpER Number of nucleotides in transcript 1 only in shared exon regions
num_nt_only_T2_in_ovlpER Number of nucleotides in transcript 2 only in shared exon regions
num_nt_ovlp_in_ovlpER Number of nucleotides shared by transcript 1 and transcript 2 in shared exon regions
total_nt_in_ovlpER Total number of nucleotides in shared exon regions
prop_nt_noOvlp_in_ovlpER Proportion of different nucleotides in shared exon regions ((num_nt_only_T1_ovlpER + num_nt_only_T2_ovlpER)/total_nt_in_ovlpER)
prop_nt_ovlp_in_ovlpER Proportion of shared nucleotides (num_nt_ovlp_in_ovlpER/total_nt_in_ovlpER)
num_nt_only_T1_in_uniqER Number of nucleotides in transcript 1 only in exon regions unique to transcript 1
num_nt_only_T2_in_uniqER Number of nucleotides in transcript 2 only in exon regions unique to transcript 2
flag_FSM Binary indicator (1,0) if transcript 1 and transcript 2 are full-splice matches (FSM) where prop_jxn_noOvlp == 0
flag_T1_ISM_of_T2 Binary indicator (1,0) if transcript 1 is an incomplete-splice match (ISM) of  transcript 2, where the junctions of transcript 1 are a sequential subset of the junctions in transcript 2
flag_T2_ISM_of_T1 Binary indicator (1,0) if transcript 2 is an incomplete-splice match (ISM) of  transcript 1, where the junctions of transcript 2 are a sequential subset of the junctions in transcript 1
flag_IR Binary indicator (1,0) if there is an intron retention event in the pair (num_IR_T1 + num_IR_T2 > 0)
flag_5_var Binary indicator (1,0) if there is a difference in 5' transcript end positions between the pair of transcripts
flag_3_var Binary indicator (1,0) if there is a difference in 3' transcript end positions between the pair of transcripts
flag_alt_DA Binary indicator (1,0) if there is an alternate donor and/or alternate acceptor in the pair (num_nt_only_T1_in_ovlpER + num_nt_only_T2_in_ovlpER > 0)
flag_alt_exon Binary indicator (1,0) if there is an alternate exon in the pair (unique exon region in either transcript)
flag_no_ovlp_nt Binary indicator (1,0) if the transcripts do not overlap and share no nucleotides (num_ovlp_nt == 0)

2 GTF Pairwise Mode - Pairwise Distance Output File

Column Name Description
gene_id Gene ID
transcript_1 Transcript ID for transcript in GTF 1 (T1)
transcript_2 Transcript ID for transcript in GTF 2 (T2)
num_jxn_only_T1 Number of junctions in transcript 1 only
num_jxn_only_T2 Number of junctions in transcript 2 only
num_jxn_same Number of junctions same in transcript 1 and transcript 2
prop_jxn_same Proportion of shared junctions (num_jxn_same/(num_jxn_only_T1 + num_jxn_only_T2 + num_jxn_same))
prop_jxn_notSame 1 - prop_jxn_same
jxn_string_T1 Piped ("|") list of all junction IDs (chr:start:end:strand) in transcript 1
jxn_string_T2 Piped ("|") list of all junction IDs (chr:start:end:strand) in transcript 2
jxn_only_T1 Piped ("|") list of junction IDs (chr:start:end:strand) in transcript 1 only
jxn_only_T2 Piped ("|") list of junction IDs (chr:start:end:strand) in transcript 2 only
jxn_same Piped ("|") list of junction IDs (chr:start:end:strand) same in transcript 1 and transcript 2
num_ER_only_T1 Number of exon regions in transcript 1 only
num_ER_only_T2 Number of exon regions in transcript 2 only
num_ER_ovlp Number of exon regions overlapping by transcript 1 and transcript 2
prop_ER_ovlp Proportion of overlapping exon regions (num_ER_ovlp/(num_ER_only_T1 + num_ER_only_T2 + num_ER_ovlp))
prop_ER_noOvlp 1 - prop_ER_ovlp
ER_only_T1 Piped ("|") list of exon region IDs in transcript 1 only
ER_only_T2 Piped ("|") list of exon region IDs in transcript 2 only
ER_ovlp Piped ("|") list of exon region IDs overlapping by transcript 1 and transcript 2
num_EF_only_T1 Number of exon EFs in transcript 1 only
num_EF_only_T2 Number of exon EFs in transcript 2 only
num_EF_ovlp Number of exon EFs overlapping by transcript 1 and transcript 2
prop_EF_ovlp Proportion of overlapping exon EFs (num_EF_ovlp/(num_EF_onlyt_T1 + num_EF_only_T2 + num_EF_ovlp))
prop_EF_noOvlp 1 - prop_EF_ovlp
EF_only_T1 Piped ("|") list of exon EF IDs in transcript 1 only
EF_only_T2 Piped ("|") list of exon EF IDs in transcript 2 only
EF_ovlp Piped ("|") list of exon EF IDs shared by transcript 1 and transcript 2
num_exon_only_T1 Number of full exons in transcript 1 only
num_exon_only_T2 Number of full exons in transcript 2 only
num_exon_ovlp Number of full exons overlapping  by transcript 1 and transcript 2
num_IR_EF_T1 Number of intron retention events in transcript 1 (where an intron of transcript 2 is entirely contained within an exon of transcript 2)
num_IR_EF_T2 Number of intron retention events in transcript 2 (where an intron of transcript 1 is entirely contained within an exon of transcript 2)
IR_EF_T1 Piped ("|") list of intron IDs (chr:start:end:strand) retained in transcript 1
IR_EF_T2 Piped ("|") list of intron IDs (chr:start:end:strand) retained in transcript 2
num_nt_ovlp Number of nucleotides overlapping in transcript 1 and transcript 2
num_nt_only_T1 Number of nucleotides in transcript 1 only
num_nt_only_T2 Number of nucleotides in transcript 2 only
num_nt_noOvlp Number of nucleotides exclusive to transcript 1 or transcript 2
total_nt Total number of nucleotides covered by either transcript 1 or transcript 2 (union)
prop_nt_noOvlp Proportion of different nucleotides ((num_nt_only_T1 + num_nt_only_T2)/total_nt)
prop_nt_ovlp Proportion of shared nucleotides (num_nt_ovlp/total_nt)
num_nt_only_T1_in_ovlpER Number of nucleotides in transcript 1 only in shared exon regions
num_nt_only_T2_in_ovlpER Number of nucleotides in transcript 2 only in shared exon regions
num_nt_ovlp_in_ovlpER Number of nucleotides shared by transcript 1 and transcript 2 in shared exon regions
total_nt_in_ovlpER Total number of nucleotides in shared exon regions
prop_nt_noOvlp_in_ovlpER Proportion of different nucleotides in shared exon regions ((num_nt_only_T1_ovlpER + num_nt_only_T2_ovlpER)/total_nt_in_ovlpER)
prop_nt_ovlp_in_ovlpER Proportion of shared nucleotides (num_nt_ovlp_in_ovlpER/total_nt_in_ovlpER)
num_nt_only_T1_in_uniqER Number of nucleotides in transcript 1 only in exon regions unique to transcript 1
num_nt_only_T2_in_uniqER Number of nucleotides in transcript 2 only in exon regions unique to transcript 2
flag_FSM Binary indicator (1,0) if transcript 1 and transcript 2 are full-splice matches (FSM) where prop_jxn_noOvlp == 0
flag_T1_ISM_of_T2 Binary indicator (1,0) if transcript 1 is an incomplete-splice match (ISM) of  transcript 2, where the junctions of transcript 1 are a sequential subset of the junctions in transcript 2
flag_T2_ISM_of_T1 Binary indicator (1,0) if transcript 2 is an incomplete-splice match (ISM) of  transcript 1, where the junctions of transcript 2 are a sequential subset of the junctions in transcript 1
flag_IR Binary indicator (1,0) if there is an intron retention event in the pair (num_IR_T1 + num_IR_T2 > 0)
flag_5_var Binary indicator (1,0) if there is a difference in 5' transcript end positions between the pair of transcripts
flag_3_var Binary indicator (1,0) if there is a difference in 3' transcript end positions between the pair of transcripts
flag_alt_DA Binary indicator (1,0) if there is an alternate donor and/or alternate acceptor in the pair (num_nt_only_T1_in_ovlpER + num_nt_only_T2_in_ovlpER > 0)
flag_alt_exon Binary indicator (1,0) if there is an alternate exon in the pair (unique exon region in either transcript)
flag_no_ovlp_nt Binary indicator (1,0) if the transcripts do not overlap and share no nucleotides (num_ovlp_nt == 0)

2 GTF Pairwise Minimum Mode - Pairwise Distance Additional Columns

Column Name Description
num_transcript_inGene_{NAME1} The number of transcripts from the first transcriptome in the given gene. NAME1 indicates the label given for the first transcriptome (default: “d1”)
num_transcript_inGene_{NAME2} The number of transcripts from the second transcriptome in the given gene. NAME2 indicates the label given for the first transcriptome (default: “d2”)
flag_{NAME1}_greater Binary indicator (1,0) if the first transcriptome (given label NAME1) has more transcripts that the second transcriptome within the given gene (num_transcript_inGene_{NAME1} > num_transcript_inGene_{NAME2}, num_transcript_inGene_{NAME1} > 0, num_transcript_inGene_{NAME2} > 0)
flag_{NAME2}_greater Binary indicator (1,0) if the second transcriptome (given label NAME2) has more transcripts that the first transcriptome within the given gene (num_transcript_inGene_{NAME2} > num_transcript_inGene_{NAME1}, num_transcript_inGene_{NAME1} > 0, num_transcript_inGene_{NAME2} > 0)
flag_match Binary indicator (1,0) if the transcriptomes have the same number of transcripts within the given gene (num_transcript_inGene_{NAME2} == num_transcript_inGene_{NAME1}, num_transcript_inGene_{NAME1} > 0, num_transcript_inGene_{NAME2} > 0)
transcript_inGene Categorical variable indicating the classification of the gene based on the transcript counts: {NAME1}_greater, {NAME2}_greater, or match
min_match_{NAME1} Transcript ID from second transcriptome (with added NAME2 suffix) that is the minimum pair of the given transcript in the first transcriptome (minimum pair based on prop_jxn_noOvlp, prop_ER_noOvlp, prop_nt_noOvlp, and num_nt_noOvlp)
flag_min_match_{NAME1} Binary indicatory (1,0) if the given pair is the minimum pair for the transcript in the first transcriptome (min_match_{NAME1} == transcript_2)
min_match_{NAME2} Transcript ID from first transcriptome (with added NAME1 suffix) that is the minimum pair of the given transcript in the second transcriptome (minimum pair based on prop_jxn_noOvlp, prop_ER_noOvlp, prop_nt_noOvlp, and num_nt_noOvlp)
flag_min_match_{NAME2} Binary indicatory (1,0) if the given pair is the minimum pair for the transcript in the second transcriptome (min_match_{NAME2} == transcript_1)
flag_RMP Binary indicatory (1,0) if the given pair is the minimum pair for both transcripts (meaning that they are reciprocal minimum matches)
num_RMP_inGene Number of reciprocal minimum pairs present in the given gene
flag_{NAME1}_tie Binary indicatory (1,0) if the transcript in first transcriptome has a tie (or more than one) minimum matches (only 1 of the ties is flagged as the minimum but both are flagged as a tie)
flag_{NAME2}_tie Binary indicatory (1,0) if the transcript in second transcriptome has a tie (or more than one) minimum matches (only 1 of the ties is flagged as the minimum but both are flagged as a tie)
flag_{NAME1}_distance_tie Piped ("|") list of transcript IDs from GTF2 that are minimum distance ties of transcript_1
flag_{NAME2}_distance_tie Piped ("|") list of transcript IDs from GTF1 that are minimum distance ties of transcript_2
flag_identical_RMP Binary indicatory (1,0) if the transcript pair is a reciprocal minimum pair AND the pair has identical coordinates
flag_FSM_RMP Binary indicatory (1,0) if the transcript pair is a reciprocal minimum pair AND the transcripts in the pair of full splice matches (FSM) of each other (or they have identical junctions but potentially differ by 5’ and 3’ end)
flag_ERS_RMP Binary indicatory (1,0) if the transcript pair is a reciprocal minimum pair AND the transcripts in the pair of exon region matches (ERS) of each other (or they have identical exon regions but potentially differ by alt. 5’/3’ ends and/or alt. donor/acceptors)
flag_ERS_noIR_RMP Binary indicatory (1,0) if the transcript pair is a reciprocal minimum pair AND the transcripts in the pair of exon region matches (ERS) of each other (or they have identical exon regions but potentially differ by alt. 5’/3’ ends and/or alt. donor/acceptors) with IR pairs excluded
flag_ERS_wIR_RMP Binary indicatory (1,0) if the transcript pair is a reciprocal minimum pair AND the transcripts in the pair of exon region matches (ERS) of each other (or they have identical exon regions but potentially differ by alt. 5’/3’ ends and/or alt. donor/acceptors) ONLY IR pairs included
num_identical_RMP_inGene Number of the transcript pairs in given gene that are reciprocal minimum pair AND have identical coordinates
num_FSM_RMP_inGene Number of transcript pairs in given gene that are reciprocal minimum pair AND are full splice matches (FSM) of each other (or they have identical junctions but potentially differ by 5’ and 3’ end)
num_ERS_RMP_inGene Number of transcript pairs in given gene that are reciprocal minimum pair AND are exon region matches (ERS) of each other (or they have identical exon regions but potentially differ by alt. 5’/3’ ends and/or alt. donor/acceptors)
num_ERS_noIR_RMP_inGene Number of transcript pairs in given gene that are reciprocal minimum pair AND are  exon region matches (ERS) of each other (or they have identical exon regions but potentially differ by alt. 5’/3’ ends and/or alt. donor/acceptors) with IR pairs excluded
num_ERS_wIR_RMP_inGene Number of transcript pairs in given gene that are reciprocal minimum pair AND are exon region matches (ERS) of each other (or they have identical exon regions but potentially differ by alt. 5’/3’ ends and/or alt. donor/acceptors) ONLY IR pairs included
prop_identical_RMP_inGene Proportion of reciprocal minimum pairs that have identical coordinates
prop_FSM_RMP_inGene Proportion of reciprocal minimum pairs that are full splice matches (FSM) of each other (or they have identical junctions but potentially differ by 5’ and 3’ end)
prop_ERS_RMP_inGene Proportion of reciprocal minimum pairs that are exon region shared (ERS) of each other (or they have identical exon regions but potentially differ by alt. 5’/3’ ends and/or alt. donor/acceptors)
prop_ERS_noIR_RMP_inGene Proportion of reciprocal minimum pairs that are  exon region matches (ERS) of each other (or they have identical exon regions but potentially differ by alt. 5’/3’ ends and/or alt. donor/acceptors) with IR pairs excluded
prop_ERS_wIR_RMP_inGene Proportion of reciprocal minimum pairs that are exon region matches (ERS) of each other (or they have identical exon regions but potentially differ by alt. 5’/3’ ends and/or alt. donor/acceptors) ONLY IR pairs included
flag_no_ovlp_nt_RMP Binary indicator (1,0) if the transcripts are reciprocal minimum pairs AND the coordinates of the transcript pair do not overlap and therefore they do have any nucleotides in common
flag_alt_exon_RMP Binary indicator (1,0) if the transcripts are reciprocal minimum pairs AND there is an alternate exon in the pair (unique exon region in either transcript)
flag_alt_DA_RMP Binary indicator (1,0) if the transcripts are reciprocal minimum pairs AND there is an alternate donor and/or alternate acceptor in the pair (num_nt_only_T1_in_ovlpER + num_nt_only_T2_in_ovlpER > 0)
flag_IR_RMP Binary indicator (1,0) if the transcripts are reciprocal minimum pairs AND there is an intron retention event in the pair (num_IR_T1 + num_IR_T2 > 0)
flag_5var_RMP Binary indicator (1,0) if the transcripts are reciprocal minimum pairs AND there is 5’ end (or TSS) variation in the pair (starts of transcripts are not the same)
flag_3var_RMP Binary indicator (1,0) if the transcripts are reciprocal minimum pairs AND there is 3’ end (or TTS) variation in the pair (ends of transcripts are not the same)
recip_min_pair_inGene Categorical variable indicating the sub-classification of the gene based on the number of transcript pairs that are reciprocal minimum pairs: reciprocal_pairs (if all possible 1-to-1 pairs are reciprocal minimum pairs), partial_reciprocal_pairs (if some but not all possible pairs are reciprocal minimum pairs), or no_reciprocal_pairs (if no reciprocal pairs are found)
flag_min_match_{NAME1}_w_tie Binary indicatory (1,0) if the given pair is a minimum pair for the transcript in the first transcriptome when including ties (transcript_2 in flag_{NAME1}_distance_tie)
flag_min_match_{NAME2}_w_tie Binary indicatory (1,0) if the given pair is a minimum pair for the transcript in the second transcriptome when including ties (transcript_1 in flag_{NAME2}_distance_tie)
flag_RMP_w_tie Binary indicatory (1,0) if the given pair is the minimum pair for both transcripts (meaning that they are reciprocal minimum matches) taking into account tied minimum pairs
num_RMP_inGene_w_tie Number of possible reciprocal minimum pairs present in the given gene with taking into account tied minimum pairs
flag_identical_RMP_w_tie (Taking into account ties) Binary indicatory (1,0) if the transcript pair is a reciprocal minimum pair AND the pair has identical coordinates
flag_FSM_RMP_w_tie (Taking into account ties) Binary indicatory (1,0) if the transcript pair is a reciprocal minimum pair AND the transcripts in the pair of full splice matches (FSM) of each other (or they have identical junctions but potentially differ by 5’ and 3’ end)
flag_ERS_RMP_w_tie (Taking into account ties) Binary indicatory (1,0) if the transcript pair is a reciprocal minimum pair AND the transcripts in the pair of exon region matches (ERS) of each other (or they have identical exon regions but potentially differ by alt. 5’/3’ ends and/or alt. donor/acceptors)
flag_ERS_noIR_RMP_w_tie (Taking into account ties) Binary indicatory (1,0) if the transcript pair is a reciprocal minimum pair AND the transcripts in the pair of exon region matches (ERS) of each other (or they have identical exon regions but potentially differ by alt. 5’/3’ ends and/or alt. donor/acceptors) with IR pairs excluded
flag_ERS_wIR_RMP_w_tie (Taking into account ties) Binary indicatory (1,0) if the transcript pair is a reciprocal minimum pair AND the transcripts in the pair of exon region matches (ERS) of each other (or they have identical exon regions but potentially differ by alt. 5’/3’ ends and/or alt. donor/acceptors) ONLY IR pairs included
num_identical_RMP_inGene_w_tie (Taking into account ties) Number of the transcript pairs in given gene that are reciprocal minimum pair AND have identical coordinates
num_FSM_RMP_inGene_w_tie (Taking into account ties) Number of transcript pairs in given gene that are reciprocal minimum pair AND are full splice matches (FSM) of each other (or they have identical junctions but potentially differ by 5’ and 3’ end)
num_ERS_RMP_inGene_w_tie (Taking into account ties) Number of transcript pairs in given gene that are reciprocal minimum pair AND are exon region matches (ERS) of each other (or they have identical exon regions but potentially differ by alt. 5’/3’ ends and/or alt. donor/acceptors)
num_ERS_noIR_RMP_inGene_w_tie (Taking into account ties) Number of transcript pairs in given gene that are reciprocal minimum pair AND are  exon region matches (ERS) of each other (or they have identical exon regions but potentially differ by alt. 5’/3’ ends and/or alt. donor/acceptors) with IR pairs excluded
prop_identical_RMP_inGene_w_tie (Taking into account ties) Proportion of reciprocal minimum pairs that have identical coordinates
prop_FSM_RMP_inGene_w_tie (Taking into account ties) Proportion of reciprocal minimum pairs that are full splice matches (FSM) of each other (or they have identical junctions but potentially differ by 5’ and 3’ end)
prop_ERS_RMP_inGene_w_tie (Taking into account ties) Proportion of reciprocal minimum pairs that are exon region matches (ERS) of each other (or they have identical exon regions but potentially differ by alt. 5’/3’ ends and/or alt. donor/acceptors)
prop_ERS_noIR_RMP_inGene_w_tie (Taking into account ties) Proportion of reciprocal minimum pairs that are  exon region matches (ERS) of each other (or they have identical exon regions but potentially differ by alt. 5’/3’ ends and/or alt. donor/acceptors) with IR pairs excluded
num_ERS_wIR_RMP_inGene_w_tie (Taking into account ties) Number of transcript pairs in given gene that are reciprocal minimum pair AND are exon region matches (ERS) of each other (or they have identical exon regions but potentially differ by alt. 5’/3’ ends and/or alt. donor/acceptors) ONLY IR pairs included
prop_ERS_wIR_RMP_inGene_w_tie (Taking into account ties) Proportion of reciprocal minimum pairs that are exon region matches (ERS) of each other (or they have identical exon regions but potentially differ by alt. 5’/3’ ends and/or alt. donor/acceptors) ONLY IR pairs included
recip_min_pair_inGene_w_tie (Taking into account ties) Categorical variable indicating the sub-classification of the gene based on the number of transcript pairs that are reciprocal minimum pairs: reciprocal_pairs (if all possible 1-to-1 pairs are reciprocal minimum pairs), partial_reciprocal_pairs (if some but not all possible pairs are reciprocal minimum pairs), or no_reciprocal_pairs (if no reciprocal pairs are found)