CV_TOO_MUCH_WORK: Possible reasons and solutions - Data2Dynamics/d2d GitHub Wiki
CV_TOO_MUCH_WORK: possible reasons and solutions
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Wild-type steady state, knockout-parameter accidentially fitted
CV_TOO_MUCH_WORK occured when fitting a model, which had 3 conditions:
- Wild-type condition for steady state calculation with no treatment
- Wild-type condition after treatment
- Knockout coundition after treatment
Accidentially I didn't comprehensively overwrite the dummy parameter "isKnockout" for specifiying wildtype (isKnockout=0) and knockout condition (isKnockout=1). So it occured in the parameter list (arPrint) and sensitivities were calculated.
After overwriting this parameter via conditions (or via values in the data table) the problem was gone.