Use LiFE to refine a candidate connectome to an optimized connectome - vistalab/vistasoft GitHub Wiki

The method solves a set of simultaneous linear equations to obtain a weight for each fascicle, and only positively weighted fascicles are retained

Fascicles in the optimized connectome all contribute to predicting the diffusion data.

Fascicles are retained only if they are needed to predict the diffusion data.