Nature vs Nuture Bibliography - tompaine2016/demographics GitHub Wiki
Links
Complex traits
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"Meta-analysis of the heritability of human traits based on fifty years of twin studies", Polderman et al 2015 (excerpts) http://www.gwern.net/docs/genetics/2015-polderman-supplement-1.pdf http://www.gwern.net/docs/genetics/2015-polderman-supplement-2.xlsx see also https://jaymans.wordpress.com/2012/12/31/all-human-behavioral-traits-are-heritable/
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"The Closest of Strangers" http://www.nytimes.com/2014/05/25/opinion/sunday/the-closest-of-strangers.html
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"Genetic and environmental influences on height from infancy to early adulthood: An individual-based pooled analysis of 45 twin cohorts" http://www.nature.com/articles/srep28496 Jelenkovic et al 2016 ; cfhttp://papers.ssrn.com/sol3/papers.cfm?abstract_id=2679002
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"Understanding and using quantitative genetic variation" Hill 2009 http://rstb.royalsocietypublishing.org/content/365/1537/73.full
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"Heritability in the genomics era - concepts and misconceptions", Visscher et al 2008 http://medicine.tums.ac.ir:803/Users/Javad_TavakoliBazzaz/Medical%20Genetics-2/Heritability%20in%20the%20genomics%20era.pdf also "Human Complex Trait Genetics in the 21st Century" http://www.genetics.org/content/202/2/377 Visscher 2016
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"Assumption-Free Estimation of Heritability from Genome-Wide Identity-by-Descent Sharing between Full Siblings" http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.0020041 Visscher et al 2006
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https://en.wikipedia.org/wiki/Genome-wide_complex_trait_analysis#Traits
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"Using Extended Genealogy to Estimate Components of Heritability for 23 Quantitative and Dichotomous Traits" Zaitlen et al 2013 http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1003520
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"Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index", Yang et al 2015; see also "Haplotypes of common SNPs can explain missing heritability of complex diseases" http://biorxiv.org/content/early/2015/07/12/022418 Bhatia et al 2015
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Obesity and genetics https://jaymans.wordpress.obesity-facts/ (see also https://en.wikipedia.org/wiki/Genome-wide_complex_trait_analysis#Anthropometric )
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"Human genetics shape the gut microbiome", Goodrich et al 2014 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255478/
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"Molecular genetic contributions to self-rated health", Harris et al 2016
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"The MC1R Gene and Youthful Looks", Liu et al 2016
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"Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan", Joshi et al 2016
Psychology
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"The Evolutionary Genetics of Personality", Penke et al 2007
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"The Evolutionary Genetics of Personality Revisited", Penke & Jokela 2016
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"Correlation and Causation in the Study of Personality", Lee 2012 http://causality.cs.ucla.edu/blog/wp-content/uploads/2012/08/lee2012.pdf
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"Genome-wide analysis of over 106,000 individuals identifies 9 neuroticism-associated loci", Smith et al 2016
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"Genetic Relations Among Procrastination, Impulsivity, and Goal-Management Ability: Implications for the Evolutionary Origin of Procrastination", Gustavson et al 2014
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"GWAS of 89,283 individuals identifies genetic variants associated with self-reporting of being a morning person", Hu et al 2016
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"The genetics of investment biases", Cronqvist & Siegal 2014 (excerpts)
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"Genetics and the placebo effect: the placebome", Hall et al 2015 (excerpts)
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"Are Political Orientations Genetically Transmitted?", Alford et al 2005 (excerpts)
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"Not by Twins Alone: Using the Extended Family Design to Investigate Genetic Influence on Political Beliefs", Hatemi et al 2010 (excerpts) see also https://jaymans.wordpress.com/2014/03/31/the-son-becomes-the-father/ "The Son Becomes The Father"
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"A Genome-Wide Analysis of Liberal and Conservative Political Attitudes", Hatemi et al 2011 (excerpts)
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"Political Attitudes Develop Independently of Personality Traits", Hatemi & Verhulst 2015
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"The Importance of Heritability in Psychological Research: The Case of Attitudes", Tesser 1993 (excerpts)
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"Not by Twins Alone: Using the Extended Family Design to Investigate Genetic Influence on Political Beliefs", Hatemi et al 2010 (excerpts)
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"The Etiology of Stability and Change in Religious Values and Religious Attendance", Button et al 2011 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045647/
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"Genetic Influence on Human Psychological Traits: A Survey", Bouchard 2004 http://humancond.org/_media/papers/bouchard04_genetic_influence_psychological_traits.pdf
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"The Genetic Architecture & Natural History of Pigmentation"
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"Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption", The Coffee and Caffeine Genetics Consortium et al 2014 (excerpts)
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How harmful is smoking during pregnancy - after controlling for the sort of people who would do that? ; see also D'Onofrio et al 2013 "Critical need for family-based, quasi-experimental designs in integrating genetic and social science research" http://people.virginia.edu/~ent3c/papers2/d%27onofrioAJPH.pdf ; Smoking is heritable but not through shared environment
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"A Genetically Informed Study of the Association Between Harsh Punishment and Offspring Behavioral Problems", Lynch et al 2006 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964497/
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"Uncovering the Hidden Risk Architecture of the Schizophrenias: Confirmation in Three Independent Genome-Wide Association Studies", Arnedo et al 2014 (press release; excerpts) see also "Biological insights from 108 schizophrenia-associated genetic loci" http://www.nature.com/nature/journal/v511/n7510/full/nature13595.html
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"Genetically low vitamin D concentrations and increased mortality: Mendelian randomisation analysis in three large cohorts", Afzal et al 2014
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on the benefits of exercise:
- "Modifiable Risk Factors as Predictors of All-Cause Mortality: The Roles of Genetics and Childhood Environment", Kujala et al 2002
- "Physical activity in adulthood: genes and mortality", Karvinen et al 2015
- "Physical Activity, Fitness, Glucose Homeostasis, and Brain Morphology in Twins", Rottensteiner et al 2015 (commentary)
Intelligence
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"A general intelligence factor in [border collie] dogs", Arden & Adams 2016
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"Chimpanzee Intelligence Is Heritable", Hopkins et al 2014 (excerpts)
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"Heritability of Neuroanatomical Shape" Ge et al 2015 http://biorxiv.org/content/early/2015/12/01/033407
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"Genomic architecture of human neuroanatomical diversity", Toro et al 2014
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"Common genetic variants influence human subcortical brain structures" Hibar et al 2015 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393366/
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"Most Reported [Candidate-Gene] Genetic Associations with General Intelligence Are Probably False Positives", Chabris et al 2012
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"Genome-wide association studies establish that human intelligence is highly heritable and polygenic" http://www.nature.com/mp/journal/v16/n10/full/mp201185a.html Davies et al 2011
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"Genetic contributions to stability and change in intelligence from childhood to old age", Deary et al 2012
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"Common DNA Markers Can Account for More Than Half of the Genetic Influence on Cognitive Abilities", Plomin et al 2013
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"The genetic architecture of pediatric cognitive abilities in the Philadelphia Neurodevelopmental Cohort", Robinson et al 2015
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"Intelligence indexes generalist genes for cognitive abilities" http://www.sciencedirect.com/science/article/pii/S0160289613001049 Trzaskowski et al 2013
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"Substantial SNP-based heritability estimates for working memory performance", Vogler et al 2014 (excerpts)
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"Results of a 'GWAS Plus': General Cognitive Ability Is Substantially Heritable and Massively Polygenic", Kirkpatrick et al 2014
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Rietveld et al 2013 supplement: http://www.gwern.netdocs/iq/2013-rietveld-supplementary-revision2.pdf
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"Childhood intelligence is heritable, highly polygenic and associated with FNBP1L", Benyamin et al 2014
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"Common genetic variants associated with cognitive performance identified using the proxy-phenotype method", Rietveld et al 2014; supplementary information
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"Molecular genetic contributions to socioeconomic status and intelligence", Marioni et al 2014
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"DNA evidence for strong genetic stability and increasing heritability of intelligence from age 7 to 12", Trzaskowski et al 2014a
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"Thinking positively: The genetics of high intelligence" (commentary)
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"Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (n=53949)", Davies et al 2015 (excerpts)
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"The genetic architecture of pediatric cognitive abilities in the Philadelphia Neurodevelopmental Cohort", Robinson et al 2015
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"A genome-wide analysis of putative functional and exonic variation associated with extremely high intelligence", Spain et al 2015
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"Genome-wide association study of cognitive functions and educational attainment in UK Biobank (n=112151)", Davies et al 2016
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"GWAS for executive function and processing speed suggests involvement of the CADM2 gene", Ibrahim-Verbaas et al 2016
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"Genome-wide association study identifies 74 [162] loci associated with educational attainment", Okbay et al 2016 (excerpts)
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"Genetic Variation Associated with Differential Educational Attainment in Adults Has Anticipated Associations with School Performance in Children", Ward et al 2014
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"A closer look at the role of parenting-related influences on verbal intelligence over the life course: Results from an adoption-based research design", Beaver et al 2014 https://www.researchgate.net/profile/Joseph_Schwartz4/publication/263663859_A_closer_look_at_the_role_of_parenting-related_influences_on_verbal_intelligence_over_the_life_course_Results_from_an_adoption-based_research_design/links/56081d3b08aea25fce3b814e.pdf
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"What Twin Studies Tell Us About the Heritability of Brain Development, Morphology, and Function: A Review", Jansen et al 2015 https://link.springer.com/article/10.1007/s11065-015-9278-9/fulltext.html
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"Genetics and intelligence differences: five special findings", Plomin & Deary 2015 http://www.nature.com/mp/journal/v20/n1/full/mp2014105a.html
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"Classical and Molecular Genetic Research on General Cognitive Ability", McGrue & Gottesman 2015 http://onlinelibrary.wiley.com/enhanced/doi/10.1002/hast.495
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"Suppressing Intelligence Research: Hurting Those We Intend to Help", Gottfredson 2005 (excerpts)
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"Large Cross-National Differences in Gene × Socioeconomic Status Interaction on Intelligence" http://www.gwern.netdocs/iq/2015-tucker-drob.pdf
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"Family environment and the malleability of cognitive ability: A Swedish national home-reared and adopted-away cosibling control study", Kendler et al 2015 http://www.pnas.org/content/112/15/4612.full
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"How Much Can We Boost IQ and Scholastic Achievement?", Jensen 1969
Social outcomes
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"Do Parents Matter?" http://gladwell.com/do-parents-matter/
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The Nurture Assumption, Harris 2009 https://dl.dropboxusercontent.com/u/85192141/2009-harris-thenurtureassumption.epub see also: http://slatestarcodex.com/2014/11/14/the-dark-side-of-divorce/ http://slatestarcodex.com/2013/06/25/nature-is-not-a-slate-its-a-series-of-levers/ http://slatestarcodex.com/2016/03/16/non-shared-environment-doesnt-just-mean-schools-and-peers/ https://jaymans.wordpress.com/2014/03/04/environmental-hereditarianism/ http://quillette.com/2015/12/01/why-parenting-may-not-matter-and-why-most-social-science-research-is-probably-wrong/
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"Demonstrating the validity of twin research in criminology", Barnes et al 2014 ; "The VNTR 2 repeat in MAOA and delinquent behavior in adolescence and young adulthood: associations and MAOA promoter activity", Guo et al 2012 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922855/ see also "Genetics of Aggression", Anholt & Mackay 2012 http://www.gwern.net/docs/genetics/2012-anholt.pdf ; "Exploring the association between the 2-repeat allele of the MAOA gene promoter polymorphism and psychopathic personality traits, arrests, incarceration, and lifetime antisocial behavior", Beaver et al 2013 https://www.researchgate.net/profile/Brian_Boutwell/publication/255700756_Exploring_the_association_between_the_2-repeat_allele_of_the_MAOA_gene_promoter_polymorphism_and_psychopathic_personality_traits_arrests_incarceration_and_lifetime_antisocial_behavior/links/0deec520393e5c8ee7000000.pdf ; Frisell et al 2011 "Violent crime runs in families: a total population study of 12.5 million individuals" http://www.sakkyndig.com/psykologi/artvit/frisell2010.pdf
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"The Role of Parenting in the Prediction of Criminal Involvement: Findings From a Nationally Representative Sample of Youth and a Sample of Adopted Youth", Beaver et al 2015 http://digitalcommons.unomaha.edu/cgi/viewcontent.cgi?article=1018&context=criminaljusticefacpub
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"Paternal Antisocial Behavior and Sons' Cognitive Ability: A Population-Based Quasiexperimental Study", Latvala et al 2014 (excerpts)
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"Genetic and environmental determinants of violence risk in psychotic disorders: a multivariate quantitative genetic study of 1.8 million Swedish twins and siblings", Sariaslan et al 2015
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Mendelian randomization https://en.wikipedia.org/wiki/Mendelian_randomization
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"Schizophrenia and subsequent neighborhood deprivation: revisiting the social drift hypothesis using population, twin and molecular genetic data", Sariaslan et al 2016 (good use of polygenic scores for confirmation)
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"Does Population Density and Neighborhood Deprivation Predict Schizophrenia? A Nationwide Swedish Family-Based Study of 2.4 Million Individuals" http://www.gwern.net/docs/genetics/2014-sariaslan-2.pdf
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"Polygenic Risk Score, Parental Socioeconomic Status, Family History of Psychiatric Disorders, and the Risk for Schizophrenia: A Danish Population-Based Study and Meta-analysis" http://www.gwern.net/docs/genetics/2015-agerbo.pdf
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"The impact of neighbourhood deprivation on adolescent violent criminality and substance misuse: A longitudinal, quasi-experimental study of the total Swedish population ", Sariaslan et al 2013 ; see also https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556483/ "Genetic and Familial Environmental Influences on the Risk for Drug Abuse: A National Swedish Adoption Study", Kendler et al 2013
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"Childhood family income, adolescent violent criminality and substance misuse: quasi-experimental total population study" http://www.gwern.net/docs/genetics/2014-sariaslan-1.pdf
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"A genome-wide approach to children's aggressive behavior: The EAGLE consortium", Pappa et al 2015 http://onlinelibrary.wiley.com/doi/10.1002/ajmg.b.32333/pdf
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"Sexual offending runs in families: A 37-year nationwide study", Langstrom et al 2015 http://ije.oxfordjournals.org/content/44/2/713.full
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"Criminal offending as part of an alternative reproductive strategy: Investigating evolutionary hypotheses using Swedish total population data", Yao et al 2014 https://www.researchgate.net/profile/Niklas_Langstroem/publication/263281358_Criminal_offending_as_part_of_an_alternative_reproductive_strategy_Investigating_evolutionary_hypotheses_using_Swedish_total_population_data/links/559ff75908ae032ef0544da6.pdf
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"Heritability, SNP- and Gene-Based Analyses of Cannabis Use Initiation and Age at Onset" https://link.springer.com/article/10.1007/s10519-015-9723-9 Minica et al 2015
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"Genetic predisposition to schizophrenia associated with increased use of cannabis" http://www.nature.com/mp/journal/v19/n11/full/mp201451a.html Power et al 2014 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382963/
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Friends are as genetically similar as fourth cousins (media)
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"Genome-Wide Estimates of Heritability for Social Demographic Outcomes" http://www.gwern.net/docs/genetics/2016-domingue.pdf
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"Polygenic Influence on Educational Attainment: New Evidence From the National Longitudinal Study of Adolescent to Adult Health", Domingue et al 2015
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"Genetic influence on family socioeconomic status and children's intelligence", Trzaskowski et al 2014 (excerpts)
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"Genetic link between family socioeconomic status and children's educational achievement estimated from genome-wide SNPs", Krapohl & Plomin 2016 (excerpts)
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"Molecular genetic contributions to socioeconomic status and intelligence", Marioni et al 2014 http://www.sciencedirect.com/science/article/pii/S0160289614000178
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"Molecular genetic contributions to social deprivation and household income in UK Biobank (n=112,151)", Hill et al 2016 (correlation graph)
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"Height, body mass index, and socioeconomic status: Mendelian randomisation study in UK Biobank", Tyrrell et al 2016
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"The Genetics of Success: How Single-Nucleotide Polymorphisms Associated With Educational Attainment Relate to Life-Course Development", Belsky et al 2016 (excerpts)
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"Poverty and Behavior: Are Environmental Measures Nature and Nurture?", Rowe & Rodgers 1997
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"Signaling and Productivity in the Private Financial Returns to Schooling", Bingley et al 2015 (highly unusual design)
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"Intelligence: Is it the epidemiologists' elusive 'fundamental cause' of social class inequalities in health?", Gottfredson 2004 (excerpts)
Pleiotropy/inter-correlation/phenome
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"An Atlas of Genetic Correlations across Human Diseases and Traits", Bulik-Sullivan et al 2015
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"Contrasting the genetic architecture of 30 complex traits from summary association data", Shi et al 2016 http://biorxiv.org/content/early/2016/01/04/035907
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"Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (n=112151) and 24 GWAS consortia", Hagenaars et al 2016
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"Detection and interpretation of shared genetic influences on 42 human traits", Pickrell et al 2016
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"LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis", Zheng et al 2016 (Web interface to scores of GWAS results, allowing combined inference over them all: LD Hub. Gets around privacy & scaling problems by using, not GCTA, but LD regression which only needs summary statistics. LD score regression is definitely the wave of the future. GCTA was king for a few years, but the inability to use summary data is killing it; in the modern context of a thousand different funding sources, 'medical ethics', & empire building driving countless genetic silos, a method must be able to work on just summary statistics if it's to have any real uptake and get n into the hundreds of thousands.)
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"The high heritability of educational achievement reflects many genetically influenced traits, not just intelligence", Krapohl et al 2014
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"Pleiotropy across academic subjects at the end of compulsory education", Rimfeld et al 2015
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"Genetics affects choice of academic subjects as well as achievement", Rimfeld et al 2016
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"DNA Evidence for Strong Genome-Wide Pleiotropy of Cognitive and Learning Abilities" Trzaskowski et al 2013 https://link.springer.com/article/10.1007/s10519-013-9594-x/fulltext.html
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"Genetically-Mediated Associations Between Measures of Childhood Character and Academic Achievement", Tucker-Drob et al 2016 http://www.gwern.net/docs/genetics/2016-tucker-drob.pdf
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"The association between intelligence and lifespan is mostly genetic", Arden et al 2015 http://ije.oxfordjournals.org/content/early/2015/07/24/ije.dyv112.full.pdf
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"Analysis of shared heritability in common disorders of the brain", Anttila et al 2016
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"Genetic relationship between 5 psychiatric disorders estimated from genome-wide SNPs", Psychiatric Genomics Consortium 2013
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"Different neurodevelopmental symptoms have a common genetic etiology", Pettersson et al 2013
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"Risk of Psychiatric and Neurodevelopmental Disorders Among Siblings of Probands With Autism Spectrum Disorders", Jokiranta-Olkoniemi et al 2016
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"Patterns of Nonrandom Mating Within and Across 11 Major Psychiatric Disorders" Nordsletten 2016 http://archpsyc.jamanetwork.com/article.aspx?articleid=2494707
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"Contrasting regional architectures of schizophrenia and other complex diseases using fast variance components analysis" http://biorxiv.org/content/early/2015/06/05/016527 Loh et al 2015
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"Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses", Okbay et al 2016
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"Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population", Robinson et al 2016
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"Systems genetics identifies a convergent gene network for cognition and neurodevelopmental disease", Johnson et al 2015 (media)
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"Large-scale genomics unveils the genetic architecture of psychiatric disorders" Gratten et al 2014 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112149/
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"Polygenic risk scores for schizophrenia and bipolar disorder predict creativity" http://www.gwern.net/docs/genetics/2015-power.pdf
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"Genetic contributions to self-reported tiredness", Deary et al 2016 (GCTA estimate is not too impressive, but the pleiotropy is interesting. What do you get when you sum a lot of weakly correlated variables? A giant difference.)
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"Association between stressful life events and psychotic experiences in adolescence: evidence for gene-environment correlations", Shakoor et al 2016
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"Physical and neurobehavioral determinants of reproductive onset and success", Day et al 2016
Rare genetics
- The Sports Gene, Epstein 2014 https://dl.dropboxusercontent.com/u/85192141/2014-epstein-thesportsgene.pdf ; see also http://www.outsideonline.com/outdoor-adventure/media/books/How-Athletes-Get-Great.html?page=all http://www.newyorker.com/magazine/2013/09/09/man-and-superman
- "The Genetic Basis of Mendelian Phenotypes: Discoveries, Challenges, and Opportunities", Chong et al 2015 (But enough about common variants & complex traits - how have we been doing in finding the causes of genetic diseases like severe Mendelian diseases? Very well.)
- "The contribution of de novo coding mutations to autism spectrum disorder", Iossifov et al 2014 (media: 1, 2; discussion; excerpts)
- "How Craig Venter is fighting ageing with genome sequencing"
- "One of a Kind: What do you do if your child has a condition that is new to science?" http://www.newyorker.com/magazine/2014/07/21/one-of-a-kind-2
- "The Muscular Dystrophy Patient and Olympic Medalist with the Same Genetic Disorder"
- "DIY Diagnosis: How an Extreme Athlete Uncovered Her Genetic Flaw" https://psmag.com/diy-diagnosis-how-an-extreme-athlete-uncovered-her-genetic-flaw-d3111a5dd376
- "Hints of genomic dark matter: rare variants contribute to schizophrenia risk"
- "A Prospective Study of Sudden Cardiac Death among Children and Young Adults", Bagnall et al 2016
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2740882/ "Genetic enhancement of cognition in a kindred with cone-rod dystrophy due to RIMS1 mutation", Sisodiya et al 2007
- "A Gene That Makes You Need Less Sleep?" (see "Heritability of Performance Deficit Accumulation During Acute Sleep Deprivation in Twins", "The Transcriptional Repressor DEC2 Regulates Sleep Length in Mammals", & "A Novel BHLHE41 Variant is Associated with Short Sleep and Resistance to Sleep Deprivation in Humans")
evolution
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"Thoroughbreds Are Running as Fast as They Can" https://fivethirtyeight.com/features/thoroughbreds-are-running-as-fast-as-they-can/ it can take centuries of intense selection to exhaust even a small bottleneck's genetic variation in racehorses. https://infoproc.blogspot.com/2013/03/its-all-in-gene-myostatin-and-racehorses.html
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"The USSR's Moose Domestication Projects Yield Mixed Results" http://www.slate.com/blogs/atlas_obscura/2013/06/21/the_ussr_s_moose_domestication_projects_yield_mixed_results.html
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"Nice Rats, Nasty Rats: Maybe It's All in the Genes" http://www.nytimes.com/2006/07/25/health/25rats.html?pagewanted=all
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"A Simple Genetic Architecture Underlies Morphological Variation in Dogs" Boyko et al 2010 http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1000451
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"Comparative analysis of the domestic cat genome reveals genetic signatures underlying feline biology and domestication", Montague et al 2014 (commentary; complex behavioral traits can be modified by relatively small shifts in many genes)
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"Rabbit genome analysis reveals a polygenic basis for phenotypic change during domestication", Carneiro et al 2014 (the power of selection - complex behaviors influenced by many small changes; excerpts)
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"When local means local: Polygenic signatures of local adaptation within whitebark pine (Pinus albicaulis Engelm.) across the Lake Tahoe Basin, USA" Lind et al 2016 http://biorxiv.org/content/early/2016/05/31/056317
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"The Rat Paths of New York" http://www.nytimes.com/2015/04/26/magazine/the-rat-paths-of-new-york.html
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"Geneticists Evolve Fruit Flies With the Ability to Count" http://www.wired.com/2012/07/flies-learn-math/
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"Artificial Selection on Relative Brain Size in the Guppy Reveals Costs and Benefits of Evolving a Larger Brain", Kotrschal et al 2013
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"Metabolic costs and evolutionary implications of human brain development", Kuzawa et al 2014 (excerpts)
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"War in the womb: A ferocious biological struggle between mother and baby belies any sentimental ideas we might have about pregnancy" https://aeon.co/essays/why-pregnancy-is-a-biological-war-between-mother-and-baby
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"Infectious causation of disease: an evolutionary perspective", Cochran et al 2000 ; see also http://discovermagazine.com/home/issues/2010/jun/03%20the%20insanity%20virus
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"Constructing genomic maps of positive selection in humans: Where do we go from here?", Akey 2009 http://genome.cshlp.org/content/19/5/711.long
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"Measuring selection in contemporary human populations", Stearns et al 2010 https://www.researchgate.net/profile/Douglas_Ewbank/publication/45462159_Measuring_selection_in_contemporary_human_populations/links/0c960516c1c8b5ef7d000000.pdf
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"Exceptional Evolutionary Divergence of Human Muscle and Brain Metabolomes Parallels Human Cognitive and Physical Uniqueness", Bozek et al 2014 http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1001871
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"The phenotypic legacy of admixture between modern humans and Neandertals", Simonti et al 2016
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"The Genetic Cost of Neanderthal Introgression" http://www.genetics.org/content/203/2/881 Harris & Nielsen 2016
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"Genome-wide patterns of selection in 230 ancient Eurasians", Mathieson et al 2015 (media)
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"Eight thousand years of [human] natural selection in Europe", Mathieson et al 2015 (Khan) ; see also EDAR https://en.wikipedia.org/wiki/Ectodysplasin_A_receptor#Derived_EDAR_allele
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"Detection of human adaptation during the past 2,000 years", Field et al 2016 (commentary)
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"Population structure of UK Biobank and ancient Eurasians reveals adaptation at genes influencing blood pressure", Galinsky et al 2016
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"Greenlandic Inuit show genetic signatures of diet and climate adaptation", Fumagalli et al 2015 http://www.gwern.net/docs/genetics/2015-fumagalli.pdf
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"Genetic Adaptation to Levels of Dietary Selenium in Recent Human History", White et al 2015 http://mbe.oxfordjournals.org/content/32/6/1507.full ; see also "Human Adaptation to Arsenic-Rich Environments" http://mbe.oxfordjournals.org/content/32/6/1544.full Schlebusch et al 2015
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"Evidence for evolution in response to natural selection in a contemporary human population", Milot et al 2011 http://www.pnas.org/content/108/41/17040.long
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"Quantitative Genetics in the Postmodern Family of the Donor Sibling Registry", Lee 2013
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Whyte et al 2016 http://www.gwern.net/docs/genetics/2016-whyte.pdf "What women want in their sperm donor: a study of more than 1000 women's sperm donor selections"
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"Why Are Some People So Smart? The Answer Could Spawn a Generation of Superbabies" http://www.wired.com/2013/07/genetics-of-iq/
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"Genetic evidence for natural selection in humans in the contemporary United States", Beauchamp 2016 ; see also https://en.wikipedia.org/wiki/Framingham_Heart_Study#Genetic_research
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"The Rhythm of the Tide: When I heard data from an island had proven humans are still evolving, I had to visit" http://nautil.us/issue/29/scaling/the-rhythm-of-the-tide-rp
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"The Indicted and the Wealthy: Surnames, Reproductive Success, Genetic Selection and Social Class in Pre-Industrial England", Clark 2009 http://www.econ.ucdavis.edu/faculty/gclark/Farewell%20to%20Alms/Clark%20-Surnames.pdf
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"Categorization of humans in biomedical research: genes, race and disease", Risch et al 2002 http://genomebiology.biomedcentral.com/articles/10.1186/gb-2002-3-7-comment2007
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"Genetic Mapping in Human Disease", Altshuler et al 2008 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694957/
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https://en.wikipedia.org/wiki/Pharmacogenomics see also http://www.economist.com/node/6795348
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"Brazil's Cancer Curse" http://mosaicscience.com/story/brazils-cancer-curse
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"A Natural Fix for A.D.H.D." http://www.nytimes.com/2014/11/02/opinion/sunday/a-natural-fix-for-adhd.html
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"Genetic Origins of Economic Development" https://growthecon.wordpress.com/2015/03/16/genetic-origins-of-economic-development/
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https://en.wikipedia.org/wiki/Human_Genetic_Diversity:_Lewontin%27s_Fallacy
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"Book Review: 'A Troublesome Inheritance' by Nicholas Wade" http://www.wsj.com/news/articles/SB10001424052702303380004579521482247869874
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"Consistent Association of Type 2 Diabetes Risk Variants Found in Europeans in Diverse Racial and Ethnic Groups", Waters et al 2010 http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1001078
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"Additive Genetic Variation in Schizophrenia Risk Is Shared by Populations of African and European Descent", de Candia et al 2013 http://www.sciencedirect.com/science/article/pii/S000292971300325X
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"Generalization and Dilution of Association Results from European GWAS in Populations of Non-European Ancestry: The PAGE Study", Carlson et al 2013 http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1001661
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http://www.gwern.net/docs/genetics/2012-ntzani.pdf "Consistency of genome-wide associations across major ancestral groups"
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"Transethnic Genetic-Correlation Estimates from Summary Statistics" http://www.sciencedirect.com/science/article/pii/S0002929716301355 Brown et al 2016
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"Population genetic differentiation of height and body mass index across Europe", Robinson et al 2015 (to quote Yvain: "Genetic differences explain 24% of between-national-populations differences in height and 8% of between-national-populations in BMI across Europe. Now that the only two massively polygenic traits that might vary among national populations have been successfully studied, I look forward to never having to read any further research of this sort ever again."; excerpts) see also https://mathii.github.io/review/2015/10/21/selection-on-height-in-europe
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"Pygmies' small stature evolved many times" http://www.sciencemag.org/news/2014/08/pygmies-small-stature-evolved-many-times ; "Adaptive, convergent origins of the pygmy phenotype in African rainforest hunter-gatherers" Perry et al 2014 http://www.pnas.org/content/111/35/E3596.full
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"National Happiness and Genetic Distance: A Cautious Exploration", Proto & Oswald 2015
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"Gene Flow by Selective Emigration as a Possible Cause for Personality Differences Between Small Islands and Mainland Populations", Ciani & Cialuppi 2011 (excerpts)
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"Demography is Destiny" https://jaymans.wordpress.com/2015/07/04/demography-is-destiny/
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"Some Uses of Models of Quantitative Genetic Selection in Social Science" Weight & Harpending 2016 http://www.gwern.net/docs/genetics/2015-weight.pdf ; see also "Western Europe, state formation, and genetic pacification" http://evp.sagepub.com/content/13/1/147470491501300114.full.pdf+html
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"...intelligence GWAS hits: Their relationship to country IQ...", Piffer 2015
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"Is there no population genetic 'support' for a racial hereditarian hypothesis?" http://humanvarieties.org/2014/10/03/is-there-no-population-genetic-support-for-a-racial-hereditarian-hypothesis/
Dysgenics
- "Sexual Selection as a Justification for Sex" http://www.unz.com/gnxp/sexual-selection-as-a-justification-for-sex/
- "Rates and Fitness Consequences of New Mutations in Humans", Keightley 2012 http://www.genetics.org/content/190/2/295.full
- "Parent-of-origin-specific signatures of de novo mutations" http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3597.html Goldmann et al 2016
- "Older fathers' children have lower evolutionary fitness across four centuries and in four populations", Arslan et al 2016 (from "The cost of inbreeding in terms of health")
- "Childhood Autism and Assortative Mating", Golden 2012
- "Heritability, Autism, & Fear of Breeding" http://www.unz.com/gnxp/heritability-autism-fear-of-breeding/
- "Estimating the Inbreeding Depression on Cognitive Behavior: A Population Based Study of Child Cohort" ; see also http://blogs.discovermagazine.com/gnxp/2013/07/genetic-diversity-and-intellectual-disability/
- "Mutation and Human Exceptionalism: Our Future Genetic Load", Lynch 2016
- "The Biodemography of Fertility: A Review and Future Research Frontiers" Mills & Tropf 2015 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577548/
- Fertility and intelligence
- "Assortative mating and differential fertility by phenotype and genotype across the 20th century", Conley et al 2016 (Dysgenics found in the USA, 1920-1955: education/intelligence polygenic scores decrease over time, inversely correlate with offspring - education/intelligence polygenic score is dropping 0.0029 SDs per year, or 0.087SD over the 30 years covered, implying that the USA genetic potential has dropped 0.28SD since 1920 or <4 IQ points. Appendix)
- "Assortative Mating, Class, and Caste", Harpending & Cochran 2015 http://www.gwern.net/docs/genetics/2015-harpending.pdf
Genetic engineering
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"Critically endangered species successfully reproduced using frozen sperm from ferret dead for 20 years: Genetic diversity of the species significantly increased providing fresh hope for the future survival of this near-extinct species" https://www.sciencedaily.com/releases/2015/08/150813130242.htm
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"Breeding a better crop seed, trait by trait" molecular breeding see also http://www.wired.com/wiredscience/2014/01/new-monsanto-vegetables/
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"Genome-wide association study of leaf architecture in the maize nested association mapping population", Tian et al 2011 https://www.researchgate.net/profile/James_Holland5/publication/49739509_Tian_F_Bradbury_PJ_Brown_PJ_Hung_H_Sun_Q_Flint-Garcia_S_et_al.._Genome-wide_association_study_of_leaf_architecture_in_the_maize_nested_association_mapping_population._Nat_Genet_43_159-162/links/0912f50f409b45bcf1000000.pdf
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"Growth, efficiency, and yield of commercial broilers from 1957, 1978, and 2005", Zuidhof et al 2014 (media; excerpts)
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"Understanding genomic selection in poultry breeding", Wolc 2014 http://emilkirkegaard.dk/en/wp-content/uploads/Understanding-genomic-selection-in-poultry-breeding.pdf
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"The Ride of Their Lives: Children prepare for the world's most dangerous organized sport" http://www.newyorker.com/magazine/2014/12/08/ride-lives
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"Tolman and Tyron: Early Research on the Inheritance of the Ability to Learn" http://emilkirkegaard.dk/en/wp-content/uploads/Tolman-and-Tryon-Early-research-on-the-inheritance-of-the-ability-to-learn.pdf
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"A short critical history of the application of genomics to animal breeding", Blasco & Toro 2014 http://www.researchgate.net/profile/Miguel_Toro/publication/264559629_A_short_critical_history_of_the_application_of_genomics_to_animal_breeding/links/540daeb
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"One Hundred Years of Statistical Developments in Animal Breeding" http://www.annualreviews.org/eprint/AEMMACidWrxGtS8eBFrT/full/10.1146/annurev-animal-022114-110733
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"Understanding the Genetics of Intelligence: Can Height Help? Can Corn Oil?", Johnson 2010 (excerpts) ; see also http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871814/
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"Cloning Cows From Steaks (and Other Ways of Building Better Cattle)"; see also http://infoproc.blogspot.com/2015/07/frontiers-in-cattle-genomics.html https://infoproc.blogspot.com/2014/08/its-all-in-gene-cows.html
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"U.S. Research Lab Lets Livestock Suffer in Quest for Profit: Animal Welfare at Risk in Experiments for Meat Industry" http://www.nytimes.com/2015/01/20/dining/animal-welfare-at-risk-in-experiments-for-meat-industry.html ; see also http://westhunt.wordpress.com/2012/02/27/typos/
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"Korea's Sooam Biotech Is the World's First Animal Cloning Factory"
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"Monkey kingdom: China is positioning itself as a world leader in primate research"
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"The Gene Hackers: A powerful new technology enables us to manipulate our DNA more easily than ever before" http://www.newyorker.com/magazine/2015/11/16/the-gene-hackers
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"Improved CRISPR-Cas9: Safe and Effective?": "High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects"/"Rationally engineered Cas9 nucleases with improved specificity"
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"The reversal test: eliminating status quo bias in applied ethics", Bostrom & Ord 2006
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http://slatestarcodex.com/2014/09/10/society-is-fixed-biology-is-mutable/
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"The Disease That Turned Us Into Genetic-Information Junkies" http://nautil.us/blog/the-disease-that-turned-us-into-genetic_information-junkies
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Wrongful birth https://en.wikipedia.org/wiki/Wrongful_birth
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"Father, Son, and the Double Helix" http://www.openthemagazine.com/article/living/father-son-and-the-double-helix#all
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"This couple says everything they were told about their sperm donor was a lie"
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"Preimplantation genetic diagnosis guided by single-cell genomics" http://www.gwern.net/docs/genetics/2013-aa.pdf
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"Embryo Selection for Cognitive Enhancement: Curiosity or Game-changer?", Shulman & Bostrom 2013 (excerpts)
-
"The Rise of the Smart Sperm Shopper: How the Repository for Germinal Choice accidentally revolutionized sperm banking" http://www.slate.com/articles/life/seed/2001/04/the_rise_of_the_smart_sperm_shopper.single.html see also https://dl.dropboxusercontent.com/u/182368464/2005-plotz-geniusfactory.epub
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"The 'Genius Babies' Grow Up: What happened to 15 children from the Nobel Prize sperm bank?" http://www.slate.com/articles/life/seed/2001/05/the_genius_babies_grow_up.html
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"In vitro eugenics" http://jme.bmj.com/content/early/2013/02/13/medethics-2012-101200.full Sparrow 2013
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"In vitro gametogenesis: just another way to have a baby?", Suter 2016 https://jlb.oxfordjournals.org/content/3/1/87
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"Introducing precise genetic modifications into human 3PN embryos by CRISPR/Cas-mediated genome editing", Kang et al 2016 (see also Liang et al 2015; both describe the CRISPR state of the art as of early 2014, 2+ years ago)
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"CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes"
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"Evolution of the Human Brain: From Matter to Mind", Hofman 2015 http://www.gwern.net/docs/iq/2015-hofman.pdf
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"Eugenics, Ready or Not", Salter
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"The Genome Project-Write", Boeke et al 2016 (media; commentary)
Overview
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"Contrarians, Crackpots, and Consensus" http://slatestarcodex.com/2015/08/09/contrarians-crackpots-and-consensus/
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"Darwin, Galton and the Statistical Enlightenment", Stigler 2010 http://www.gwern.net/docs/statistics/2010-stigler.pdf
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"Measure for Measure: The strange science of Francis Galton"
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"The Social and Political Views of American Professors", Gross & Simmons 2007 http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.147.6141&rep=rep1&type=pdf
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"Whither the Blank Slate? A Report on the Reception of Evolutionary Biological Ideas among Sociological Theorists", Horowitz et al 2014 (media; excerpts)
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"Political Diversity Will Improve Social Psychological Science", Duarte et al 2014 (excerpts)
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"How Napoleon Chagnon Became Our Most Controversial Anthropologist" http://www.nytimes.com/2013/02/17/magazine/napoleon-chagnon-americas-most-controversial-anthropologist.html?pagewanted=all
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"The IQ Controversy, the Media and Public Policy" https://en.wikipedia.org/wiki/The_IQ_Controversy,_the_Media_and_Public_Policy_(book) Fulltext: http://emilkirkegaard.dk/en/wp-content/uploads/The-I.-Q.-Controversy-The-Media-and-Public-Policy-Stanley-Rothman-323p_0887381510.pdf
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"Mainstream Science on Intelligence" https://en.wikipedia.org/wiki/Mainstream_Science_on_Intelligence
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"2013 survey of expert opinion on intelligence" Rindermann et al 2013 http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.695.3163&rep=rep1&type=pdf
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"Survey of Expert Opinion on Intelligence: Causes of International Differences in Cognitive Ability Tests" Rindermann et al 2016 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804158/
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"Ethics: Taboo genetics" http://www.nature.com/news/ethics-taboo-genetics-1.13858
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Cochran on publishing the Ashkenazi intelligence hypothesis http://boards.straightdope.com/sdmb/showpost.php?p=13724510&postcount=133
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"We can’t ignore the evidence: genes affect social mobility" http://www.prospectmagazine.co.uk/magazine/we-cant-ignore-the-evidence-genes-affect-social-mobility
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The end of environmental inequality means the rise of genetic inequality http://blogs.discovermagazine.com/gnxp/2011/08/the-end-of-environmental-inequality-means-the-rise-of-genetic-inequality/
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"Interview of Linda S. Gottfredson, by Howard Wainer & Daniel Robinson" 2007 http://www.udel.edu/educ/gottfredson/reprints/2007gottfredsoninterview.pdf
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"Why can't we talk about IQ?" http://www.politico.com/story/2013/08/opinion-jason-richwine-95353_Page2.html
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"Dalton Conley Answers Your “Parentology” Questions" http://freakonomics.com/2014/03/26/dalton-conley-answers-your-parentology-questions/
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"Tutankhamen's Blood" https://medium.com/matter/tutankhamuns-blood-9fb62a68597b
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"Eske Willerslev Is Rewriting History With DNA" http://www.nytimes.com/2016/05/17/science/eske-willerslev-ancient-dna-scientist.html
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"Is crime genetic? Scientists don't know because they're afraid to ask" https://www.bostonglobe.com/ideas/2016/03/06/crime-genetic-scientists-don-know-because-they-afraid-ask/3lhGUVuNsfdJXjvhtaxPHN/story.html
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"Cosmic Horror: In which we confront the terrible racism of H. P. Lovecraft"
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http://people.virginia.edu/~ent3c/papers2/three_laws.pdf "Three Laws of Behavior Genetics and What They Mean", Turkheimer 2000
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"Epidemiology, genetics and the 'Gloomy Prospect': embracing randomness in population health research and practice", Smith 2011 (excerpts)
-
"Word Reading Fluency: Role of Genome-Wide Single-Nucleotide Polymorphisms in Developmental Stability and Correlations With Print Exposure", Harlaar et al 2014 http://onlinelibrary.wiley.com/doi/10.1111/cdev.12207/full
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"G = E: What GWAS Can Tell Us about the Environment" Gage et al 2016 http://journals.plos.org/plosgenetics/article/asset?id=10.1371/journal.pgen.1005765.PDF
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"Do People Make Environments or Do Environments Make People?", Rowe 2001 http://www.gwern.net/docs/genetics/2001-rowe.pdf
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"Top 10 Replicated Findings From Behavioral Genetics", Plomin et al 2016
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"Why Behavioral Genetics Matters: Comment on Plomin et al. (2016)", Lee & McGue 2016 http://moscow.sci-hub.bz/5df997543c7b2e72b909cb405ea58aaa/10.1177%401745691615611932.pdf
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"On the genetic architecture of intelligence and other quantitative traits", Hsu 2014
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Behavioral Genetics, Plomin et al 2012 http://www.gwern.net/docs/genetics/2012-plomin-behavioralgenetics.pdf
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"What 2,500 Sequenced Genomes Say About Humanity's Future" http://www.wired.com/2015/09/power-1000-genomes/
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"My Genome, My Self" http://www.nytimes.com/2009/01/11/magazine/11Genome-t.html?_r=2&pagewanted=all