UniProt - sporedata/researchdesigneR GitHub Wiki
General description
The Universal Protein Resource (UniProt) is the world’s leading comprehensive, freely accessible, and high-quality resource of protein sequence and functional annotation data.
There exist four UniProt databases:
- The UniProt Reference Clusters (UniRef) - Clusters of protein at different stages (100%, 90%, and 50%) of identity.
- The UniProt Sequence Archive (UniParc) - A non-redundant archive of publicly available protein sequences seen across different databases.
- The UniProt Knowledgebase (UniProtKB) - A key resource for gathering functional protein data, characterized by its accurate, comprehensive, and consistent annotations. UniProtKB is divided into two sections:
- UniProtKB/Swiss-Prot: Features manually annotated records that include information derived from literature reviews and computational analyses evaluated by curators.
- UniProtKB/TrEMBL: Contains records that have been computationally analyzed and are pending comprehensive manual annotation.
Related publications
- Mechanisms of GDF-5 action during skeletal development
- Requirement of a novel gene, Xin, in cardiac morphogenesis
- Formate assay in body fluids: application in methanol poisoning
- A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo
- Stromal cells mediate retinoid-dependent functions essential for renal development
- Inhibition of in vitro enteric neuronal development by endothelin-3: mediation by endothelin B receptors
- JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development
- The amino acid sequence of Neurospora NADP-specific glutamate dehydrogenase. Peptic and chymotryptic peptides and the complete sequence
- The hematopoietic-specific adaptor protein gads functions in T-cell signaling via interactions with the SLP-76 and LAT adaptors
- Rule of antibody structure. The primary structure of a monoclonal IgG1 immunoglobulin (myeloma protein Nie), I: purification and characterization of the protein, the L- and H-chains, the cyanogen bromide cleavage products, and the disulfide bridges
Data access
More information about UniProt can be found at https://www.uniprot.org/