NACC - sporedata/researchdesigneR GitHub Wiki

General description

The National Alzheimer’s Coordinating Center (NACC) was designed to modernize the collection, integration, and sharing of data to advance Alzheimer’s research. NACC comprises one of the largest, oldest, and most potent Alzheimer’s datasets and facilitates collaborative research between more than 42 Alzheimer’s Disease Research Centers (ADRCs) across the US.

Also, the NACC provides a valuable resource for both exploratory and explanatory Alzheimer's disease research and has developed and maintains an extensive relational database of standardized clinical and neuropathological research data.

Linkages

The NACC partners with the Alzheimer's Disease Genetics Consortium (ADGC), the National Centralized Repository for Alzheimer's Disease and Related Disorders (NCRAD), and the NIA Genetics of Alzheimer's Disease Data Storage Site (NIAGADS) to build a one-stop-shop for all ADRC data, the “Data Front Door” (DFD).

Related publications

• Version 3 of the Alzheimer Disease Centers’ Neuropsychological Test Battery in the Uniform Data Set (UDS)
• Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
• Expanded Demographic Norms for Version 3 of the Alzheimer Disease Centers' Neuropsychological Test Battery in the Uniform Data Set
• Multimodal deep learning for Alzheimer’s disease dementia assessment
• Generalizable deep learning model for early Alzheimer's disease detection from structural MRIs
• Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report
• New insights into the genetic etiology of Alzheimer’s disease and related dementias
• Primary age-related tauopathy (PART): a common pathology associated with human aging
• Black and White individuals differ in dementia prevalence, risk factors, and symptomatic presentation
• The Revised National Alzheimer's Coordinating Center's Neuropathology Form-Available Data and New Analyses

Data access

More information about NACC can be found at https://naccdata.org/

To access NACC data, visit https://naccdata.org/requesting-data/nacc-data/