CCDI MTP - sporedata/researchdesigneR GitHub Wiki

General description

The Molecular Targets Platform is an National Cancer Institute (NCI) -supported instance of the Open Targets Platform with a focus on preclinical pediatric oncology data. It is a tool that supports the identification and prioritization of molecular targets expressed in childhood cancers. The CCDI Molecular Targets Platform (CCDI-MTP) allows researchers to browse and identify associations between molecular targets, diseases, and drugs specific for childhood cancers.

The Molecular Targets Platform expands on the Open Targets Platform by incorporating additional resources and analyses. These include:

• The FDA Pediatric Molecular Target Lists (FDA PMTL).
• Analyses of pediatric cancer datasets from the Open Pediatric Cancer (OpenPedCan) initiative at the Children's Hospital of Philadelphia.
  • Open Pediatric Brain Tumor Atlas (OpenPBTA)
  • Gabriella Miller Kids First (Kids First) Neuroblastoma.
  • Therapeutically Applicable Research to Generate Effective Treatments (TARGET)

Data access

More information about CCDI-MTP can be found at https://moleculartargets.ccdi.cancer.gov/