AgingResearchBiobank - sporedata/researchdesigneR GitHub Wiki

General description

The AgingResearchBiobank was designed to provide a state-of-the-art inventory system for storing, maintaining, and distributing biospecimens and associated data from numerous NIA-funded longitudinal studies on aging and clinical trials with the broader scientific community.

The AgingResearchBiobank also fosters compliance with NIH/NIA resources sharing policies to help extend the healthy, active years of life for the world's fast-growing population of older adults and hosts and distributes imaging data for some of our study collections.

Related publications

• Energy requirements in nonobese men and women: results from CALERIE
• Dietary adherence to long-term controlled feeding in a calorie-restriction study in overweight men and women
• Effects of 2 years of caloric restriction on oxidative status assessed by urinary F2-isoprostanes: The CALERIE 2 randomized clinical trial
• Metabolic and behavioral compensations in response to caloric restriction: implications for the maintenance of weight loss
• Peripheral interleukin-6 levels and working memory in non-obese adults: A post-hoc analysis from the CALERIE study
• Effect of 6-month calorie restriction and exercise on serum and liver lipids and markers of liver function
• Persistence of weight loss and acquired behaviors 2 y after stopping a 2-y calorie restriction intervention
• Quantification of the pace of biological aging in humans through a blood test, the DunedinPoAm DNA methylation algorithm
• Change in self-efficacy, eating behaviors and food cravings during two years of calorie restriction in humans without obesity
• A 2-Year Randomized Controlled Trial of Human Caloric Restriction: Feasibility and Effects on Predictors of Health Span and Longevity

Data access

More information about AgingResearchBiobank can be found at https://agingresearchbiobank.nia.nih.gov/