07.Health economics01.Cost utility analysis - sporedata/researchdesigneR GitHub Wiki

1. Use cases: in which situations should I use this method?

2. Input: what kind of data does the method require?

  • Effectiveness: can be conducted using meta-analyses, observational datasets coupled with causal models, or a randomized trial. Using a high-quality trial has the advantage of generating unbiased measures of effectiveness, but the disadvantage of the trial being an environment that might not represent the real world. In other words, randomized trials will often have protocols that do not match the day-to-day clinical reality for a given condition or technology.

3. Algorithm: how does the method work?

Model mechanics

Reporting guidelines for Methods

  • Consolidated Health Economic Evaluation Reporting Standards (CHEERS) Statement [1].
  • Economic evaluations alongside clinical trials [2].

Data science packages

Suggested companion methods

Learning materials

  1. Books
    • Meta-Analysis, Decision Analysis, and Cost-Effectiveness Analysis: Methods for Quantitative Synthesis in Medicine [3].
    • Bayesian Methods in Health Economics [4].
    • Bayesian Cost-Effectiveness Analysis with the R package BCEA (Use R!) [5].
    • Metodi statistici per la valutazione economica delle tecnologie sanitarie [6].
    • Cost Effectiveness Modelling for Health Technology Assessment: A Practical Course [7].
  2. Articles
    • Cost-Effectiveness Analysis in R Using a Multi-state Modeling Survival Analysis Framework [8].

4. Output: how do I interpret this method's results?

Mock conclusions or most frequent format for conclusions reached at the end of a typical analysis.

Tables, plots, and their interpretation

5. SporeData-specific

Templates

Data science functions

References

[1] Husereau D, Drummond M, Petrou S, Carswell C, Moher D, Greenberg D, Augustovski F, Briggs AH, Mauskopf J, Loder E, CHEERS Task Force. Consolidated health economic evaluation reporting standards (CHEERS) statement. Cost Effectiveness and Resource Allocation. 2013 Dec 1;11(1):6.

[2] Ramsey S, Willke R, Briggs A, Brown R, Buxton M, Chawla A, Cook J, Glick H, Liljas B, Petitti D, Reed S. Good research practices for cost‐effectiveness analysis alongside clinical trials: the ISPOR RCT‐CEA Task Force report. Value in health. 2005 Sep;8(5):521-33.

[3] Petitti, D. B. (2000). Meta-analysis, decision analysis, and cost-effectiveness analysis: methods for quantitative synthesis in medicine (No. 31). OUP USA.

[4] Baio, G. (2012). Bayesian methods in health economics. CRC Press.

[5] Baio G, Berardi A, Heath A. Bayesian cost-effectiveness analysis with the R package BCEA. New York: Springer; 2017 May 25.

[6] Baio G. Metodi statistici per la valutazione economica delle tecnologie sanitarie. Aracne; 2010 dicembre 1).

[7] Edlin R, McCabe C, Hulme C, Hall P, Wright J. Cost effectiveness modelling for health technology assessment: a practical course. Springer; 2015 Aug 11.

[8] Williams C, Lewsey JD, Briggs AH, Mackay DF. Cost-effectiveness analysis in R using a multi-state modeling survival analysis framework: a tutorial. Medical Decision Making. 2017 May;37(4):340-52.

[9] Xu X, Lazar CM, Ruger JP. Micro-costing in health and medicine: a critical appraisal. Health Economics Review. 2021 Dec;11(1):1-8.

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