Database Constructor Alternates - schotime/NPoco GitHub Wiki
Using .NET Core you will have to specify your constructor like the following. Noting here that SqlServer2012
doesn't mean it won't work on Sql Server 2016 but that the this is the minimum syntax supported version.
var db = new Database("server=${servername};database=${databasename};user id=${userid};password=${password}",
DatabaseType.SqlServer2012,
System.Data.SqlClient.SqlClientFactory.Instance);