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Significance for the scores: SEA search server determined a score of greater than .6 as significant.
SPACE ATC code prediction used a p value. TEST EPA toxicity - values greater than .5 are determined to be significant.

Predictive Power of Various Servers listed on this page:

For Rosetta- the binding energy correlation between experimental small molecule binding with virtual binding is R=.63 Correlation and prediction quality vary largely with the type of protein

SEA Search Server-- Tested three unexpected results and confirmed these

SPACE ATC code prediction-- AOC for ROC curve was .946

SWISS ADME-

GI Adsorption- 88% BBB- 92% Skin Permeability- 80% cytochrome inhibitor- 72%

EPA TEST toxicity software- oral LD50- .788 Nearest Neighbor- .557 Consensus .63

Developmental- hierarchial- .72 single model - .73 nearest neighbor - .795 consensus - .772

Ames- hierarchial- .76 nearest neighbor - .77 consensus - .77