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Welcome to the orthocore wiki!

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Given a set of bacterial genomes, orthocore is a perl pipeline that allows you to obtain the core genome set and use it to construct a phylogenomic tree. Phylogenomic trees may provide better resolution than single locus trees.

Orthocore perform the following tasks:

  1. Obtain best hits for each gene (blastp)
  2. Obtains a list of best bidirectional hits
  3. Align (MUSCLE)
  4. Shave (Gblocks)
  5. Concatenates
  6. Gives you a quicktree and a matrix
  7. Aditionally you can consult functions.