File Format: Pathways - lrgr/explosig-docker GitHub Wiki
The pathways file specifies the genes that belong to each pathway in a pathway group. This file should contain the following columns:
Pathway: The name of the pathway.Gene Symbol: The gene ID.Core: Whether this gene is a "core" pathway gene. EitherTRUEorFALSE.Gene Description: A description of the gene.Location: The gene's chromosome location.
An example of this file is as follows:
| Pathway | Gene Symbol | Core | Gene Description | Location |
|---|---|---|---|---|
| Base Excision Repair (BER) | ALKBH1 | FALSE | alkB homolog 1, histone H2A dioxygenase | 14q24.3 |
| Base Excision Repair (BER) | APEX1 | TRUE | apurinic/apyrimidinic endodeoxyribonuclease 1 | 14q11.2 |
| Fanconi Anemia (FA) | APITD1 | FALSE | apoptosis-inducing, TAF9-like domain 1 | 1p36.22 |
| Fanconi Anemia (FA) | BARD1 | FALSE | BRCA1 associated RING domain 1 | 2q35 |
| Fanconi Anemia (FA) | BLM | FALSE | Bloom syndrome, RecQ helicase-like | 15q26.1 |
| ... | ... | ... | ... | ... |