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Welcome to the sim_reg wiki!

sim_reg is a MATLAB implementation of a "similarity-weighted" variant of the popular Iterative Closest Point (ICP) image registration algorithm. More specifically, sim_reg runs ICP and at each iteration calculates a local similarity metric between scene and model images, using those values as weights for the linear regression step of registering the corresponding point clouds.

The target application is alignment and correspondence of "functional" and "anatomical" images from the the same plane of neural fluorescence imaging, taken at different time points.

For an overview of the structure of the program, see the Structure page

For a conceptual overview of the algorithm, see the Algorithm page

For details regarding a specific function, see that function's page; any function without a page is not currently part of the pipeline