AboutUs - kpeaton/altanalyze_wikitest GitHub Wiki
About Us
AltAnalyze is an open-source software project principally run by developers in the Nathan Salomonis laboratory at Cincinnati Children's Hosptial Medical Center and the University of Cincinnati. This project began in the laboratory of Bruce Conklin at the Gladstone Institutes. The goal of this project is to provide easy to use applications for biologists with little computational training as well as computational biologists for the analysis of microarray and ultimately RNA sequencing datasets.
Our hope, is that AltAnalyze and associated tools will help researchers to provide greater biological insight and uncover new mechanisms that regulate cellular biology. Thus, much of the focus of AltAnalyze is on functional interpretation of results in addition to the development of new analytical methods to evaluate alternative splicing and regulatory control.
If you would like to contribute to AltAnalyze development or to the documentation on this site, we welcome your contributions.
Citing AltAnalyze
The following citations are most relevant:
AltAnalyze and DomainGraph: analyzing and visualizing exon expression data. Emig D, Salomonis N, Baumbach J, Lengauer T, Conklin BR, Albrecht M. Nucleic Acids Res. 2010 Jul 1;38 Suppl:W755-62. Epub 2010 May 31.
Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiation. Salomonis N, Schlieve CR, Pereira L, Wahlquist C, Colas A, Zambon AC, Vranizan K, Spindler MJ, Pico AR, Cline MS, Clark TA, Williams A, Blume JE, Samal E, Mercola M, Merrill BJ, Conklin BR. Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10514-9. Epub 2010 May 24.
Alternative splicing in the differentiation of human embryonic stem cells into cardiac precursors. Salomonis N, Nelson B, Vranizan K, Pico AR, Hanspers K, Kuchinsky A, Ta L, Mercola M, Conklin BR. PLoS Comput Biol. 2009 Nov;5(11):e1000553. Epub 2009 Nov 6.
Other Articles
Development Team
| Name | Role | Affiliation |
|---|---|---|
| Nathan Salomonis | Principle Investigator | CCHMC |
| Dorothea Emig | Software Design | Max Planck Institute |
| Mario Albrecht | Software Design | Max Planck Institute |
| Kristina Hanspers | Software Design | Gladstone Institutes |
| Alex Pico | Software Design | Gladstone Institutes |
| Bruce Conklin | Advisor | Gladstone Institutes |