Some REPLs may require configuration in order to work properly with vim-slime.

radian

If you send code to radian, please put

options(radian.auto_match = FALSE)

in $HOME/.config/radian/profile, in order to stop radian from auto-closing parentheses that will be closed on following lines (thus generating an error).

IPython

If you are sending code to IPython, you may want to set InteractiveShell.autoindent IPython option to False, in order to prevent IPython from inserting indents on top of the ones already present in your python file (thus duplicating indentation levels and generating IndentationError: unexpected indent errors).

To remove newlines inserted by IPython between commands, set the InteractiveShell.separate_in option to ''.