RUFUS HYPE - jandrewrfarrell/RUFUS GitHub Wiki

"Andrew Farrell (Boston College, USA) presented RUFUS, an ingenious algorithm for detecting differences between two samples that requires no reference sequence. RUFUS promises to have many applications, from cancer to RNA editing." - Gustavo Glusman

"RUFUS > NIKS" - Will Richards (NIKS detection is based on static cutoffs, where as RUFUS use a Bayesian detection method, thus NIKS will only detect homozygous/haploid mutations between two samples. NIKS is not capable of detecting any of the copy number variations or heterozygous variations detected by RUFUS.)