Gene ‐ Pathway - hisl6802/ClusteringToolbox GitHub Wiki

Gene to Pathway 🧬

The pathways associated with a set of genes can provide insights into the particular biological responses that occurring when a gene is differentially expressed. This function streamlines the detection of up to the top 10 pathways listed in the genes database entry in KEGG, allowing users to rapidly understand the pathway responses.

Input data sheet

Gene	Log2FC	FDR
Mif	-2.67	3.38e-15
Ihh	-1.99	2.77e-15

Output data sheet

Gene	Log2FC	FDR	P1	P2	P3	P4	P5	P6	P7	P8	P9	P10
Mif	-2.67	3.38e-15	mmu00350 Tyrosine metabolism	mmu00360 Phenylalanine metabolism	mmu01100 Metabolic pathways
Ihh	-1.99	2.77e-15	mmu04340 Hedgehog signaling pathway	mmu05205 Proteoglycans in cancer