Enzyme Look Up - hisl6802/ClusteringToolbox GitHub Wiki
Rapidly getting enzymes associated with found compounds in a pathway
After pathway analysis it is often interesting to understand the associated enzymes that the detected compounds are associated with. However, with multiple compounds per pathway and multiple enzymes per compound this becomes infeasible. Therefore, this functionality automates the determination of the enzymes present in a pathway.
Input File
| Pathway |
Pathway Total |
Hits.total |
Hits.sig |
Gamma |
Cpd.Hits |
| Glycolysis |
23 |
2 |
1 |
1 |
C00036 |
| Citrate cycle |
16 |
2 |
1 |
1 |
C00036 |
| Fructose and mannose metabolism |
18 |
3 |
1 |
1 |
C02985 |
| Primary bile acid biosynthesis |
46 |
4 |
1 |
1 |
C01921 |
| Steroid hormone biosynthesis |
77 |
29 |
1 |
1 |
C05284;C05302;C05290;C05295;C05140 |
Output File
| Pathway |
Pathway Total |
Hits.total |
Hits.sig |
Gamma |
Cpd.Hits |
Enzyme #s |
| Glycolysis |
23 |
2 |
1 |
1 |
C00036 |
['1.1.1.37'], ... |
| Citrate cycle |
16 |
2 |
1 |
1 |
C00036 |
['1.1.1.37'], ... |
| Fructose and mannose metabolism |
18 |
3 |
1 |
1 |
C02985 |
['2.7.1.52'], ... |
| Primary bile acid biosynthesis |
46 |
4 |
1 |
1 |
C01921 |
['2.3.1.65'], ... |
| Steroid hormone biosynthesis |
77 |
29 |
1 |
1 |
C05284 |
['1.1.1.62'], ... |
|
|
|
|
|
C05302 |
['2.1.1.6'], ... |
|
|
|
|
|
C05290 |
['1.14.14.14'] |
|
|
|
|
|
C05295 |
['1.14.14.14'] |
|
|
|
|
|
C05140 |
['1.1.1.145'], '5.3.3.1'] |
Note: When you have more than 1 sheet (i.e., output from peaks-to-pathways) you will get multiple sheets with different output tables