SARS Examples - graph-genome/Schematize GitHub Wiki

Example of SARS and SARS-CoV2

So far, we described how insertion, deletion and inversion are shown in the Pantograph. Now, we move into the real-world example of SARS and SARS-CoV2. The figure below shows the attempted alignment between SARS and SARS-CoV2.

This shows sequenced SARS-CoV2 genomes seem to have longer common sequence since most paths present on the same component (caveat: one component includes several bins here), while the upper right and lower left separation indicates very little overlap between the two types of coronavirus.

Interestingly, “sars-bat_MG772933” genome has shared sequences with either SARS-CoV2 or SARS-ExoN1. Pantograph Browser provides an insight into how genome sequences are shared or divergent between samples on Pangenome Sequence.

Figure: Very preliminary results on an attempted alignment between SARS and SARS-CoV2. Dark grey cells represent sequences present at a locus for an individual. The upper right and lower left separation indicate very little overlap between the two types of coronavirus. The first component with a bright green Arrival Link is shared between all SARS-ExoN1 and some SARS-CoV2 strains.

Visualization of Public Sequence Resource Data

If you are checking out our deploy branch, you can see our proud visualization a subset of the graphical pangenome of COVID-19 from the Public Sequence Resource. Thanks to the hard work of the PubSeq team, we are able to directly visualize their data.