Supplements: Nootropic Stack - feralcoder/shared GitHub Wiki

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I have multiple programs I use in combination to achieve different things: Supplements: Daily Baseline Supplements: Metabolism (placeholder) Supplements: Occams Workout Stack

Nootropic Stack

Some of this stack will be harnessed on workout days, as many of these improve capacity to work or muster effort.

Much info here is sourced from https://nootropicsexpert.com/. Thank you, experts, this is a great resource!

Info also collected more skeptically from the larger internet, preserving warnings, interactions, and indications.

Baseline

These fundamentals are my baseline daily and probably won't change as I experiment with the rest of the stack.

DHA

The dominant fatty acid in brain and retina, by far. This is the best and least abundant Omega-3 in fish oil. It's best to consume more DHA than EPA (the most abundant Omega-3 in fish oil), to overcome transport competition. Every aspect of brain health depends on adequate DHA supply. Dosage: 1,000 mg/day.

Replace Brain Quick / Body Quick

I had great workout and project-time results with this pre-formulated stack, but it was too expensive and is now hard to even find. Time to make my own.

Per-Pill (x2-4 / serving):

  • Niacin (Niacinamide) 10mg
  • B6 (Pyridoxal 5 Phosphate) 12.5mg
  • Folate (Calcium 5-MTHF) 200mcg
  • B12 (Methylcobalamin) 500mcg
  • Pantothenic Acid (Calcium D-Pantothenate) 20mg

Plus Mix of:

  • Cordyceps Sineseis
  • Choline Bitartrate
  • L-Glutamine
  • Eleuthero Root (Eleutherococcus Senticosus
  • L-Tyrosine
  • White Willow Bark (Salix Alba)
  • Phosphatidylserine
  • DMAE Bitrartrate (2-dimethylaminoethanol)
  • Ginkgo Biloba Leaf
  • Yoacanca Africana Seed extract
  • Huperzia Serrata extract
  • Guarana Seed extract
  • RS ALA

Already Taking

These ones I don't need to incorporate into my nootropic / workout stack, because I'm already taking them in my routine supplement stacks.

Supplements: Daily Baseline:

  • B3 (Niacin, Niacinamide) 10mg
  • B5 (Pantothenic Acid as Calcium D-Pantothenate) 20mg
  • B6 (Pyridoxal 5 Phosphate) 12.5mg
  • B9 (Folate as Calcium 5-MTHF) 200mcg
  • B12 (Methylcobalamin) 500mcg
  • Ginkgo Biloba Leaf

Supplements: Metabolism Stack:

  • L-Glutamine
  • RS ALA

Resume These?

I have them, but should research again what they do and how:

  • Cordyceps Sineseis
  • Chaga mushroom
  • Reishi mushroom

Source These?

Investigate these and decide whether to add them and how:

  • Guarana Seed extract
  • Yoacanca Africana Seed extract
  • Eleuthero Root (Eleutherococcus Senticosus
  • White Willow Bark (Salix Alba)

Current Replacements on Deck

L-Tyrosine 500 mg:

Precurser to L-Dopa, which precurses dopamine, norepinephrine, and epinephrine. Precurser to thyroxine (main thyroid hormone). Potentiated by amino acids like tryptophan to cross blood-brain barrier. Mood elevator, anti-anxiety, protects brain nerve cells from neourotoxins. L-Dopa: Increases libido, testosterone, enhances memory and learning retention. Reported to increase HGH. Dopamine: Libido, memory, focus, goal-oriented concentration, a mood elevator and anti-depressant. Norepinephrine: helps with alertness, working memory, focus, and executive function. L-Tyrosine: supports healthy glandular function and stress response because it helps with the synthesis of thyroid hormone and epinephrine. Military studies have found: useful for cold, fatigue, prolonged work, stress, sleep deprivation, and those suffering with hypothyroidism. Dosage (N-Acetyl L-Tyrosine): 300 – 500 mg dosed 2 or 3-times per day

Huperzine A 200mcg:

Extracted from Chinese club moss Huperzia Serrata. An acetylcholinesterase inhibitor, boosting acetylcholine. Promotes memory, retention, cognition, and lucid dreaming. Dosage: 200 mcg every 2-3 days. CAUTION: 24-hour half-life, so build-up can be a problem, resulting in acetylcholine accumulation.

Vinpocetine 10mg:

Derived from periwinkle. Enhances brain blood flow, as a vasodilator and a blood thinner. Boosts oxygen and glucose to the brain. Easily crosses blood-brain barrier. Maintains healthy levels of neurotransmitters, promoting concentration, focus, and memory. Nootropic: 10 mg 3x/day.

DMAE Bitartrate 150mg:

Prevents choline metabolism, boosting choline levels in the brain. Boosts alertness, mood, and memory. Some report energy boosts. Others hyperactivity, loss of focus and motivation, and depression. Most negative reports are associated with high dosages and prolonged use. Start at 50 mg / day, going up to 200 mg.

Phosphatidylserine 100mg:

Phospholipid in all cells, most concentrated in brain cell wall membranes. Helps with storage and release of neurotransmitters, and the activity of their receptors. Production declines with age, supplementation is critical. Boosts cognition, focus, memory, and recall. Dosage: 100 - 300 mg / day.

Citicoline (CDP-Choline) 250mg:

Highly bioavailable source of choline, easily crosses blood-brain barrier. Metabolized to form choline and cytidine. Aids in synthesis of acetylcholine. Cytidine converts to uridine, a necleotide important to neural membrane synthesis. Boosts other nootropics, especially racetams. Dosage: 250 - 750 mg / day.

Alpha-Glyceryl Phosphoryl (AGP-)Choline (or Alpha-GPC)

Precursor to Acetylcholine and Phosphatadylcholine - acetylcholine is actually a byproduct of other AGPC metabolism. Easily crosses blood-brain barrier. AGPC itself has benefits aside from Acetylcholine synthesis, including HGH production, increasing workout energy and muscle recovery. Serves as a reservoir for Acetylcholine in the blood, and boosts nerve growth factor receptors in the brain. Can slow degenerative brain diseases by protecting brain cells from catabolic processes. Dosage : 600 mg