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This presenilin gene is at the beginning of a chromosomal contig and is missing the first 28 amino acids. The protein sequence is derived form EST DDB0163023 (SSE544). There is a 1 nt difference between the ESTs and the genome sequence, predicting a Threonine at position 30 instead of a Proline as shown here. Sequence similarity shows that the EST sequence is correct.

MLIPEDDKLDDEKMINIAKKLWFIGFFFLPWVWLINILYFIPYRNSLNDKVKWYLKFSLI
GFLGYSTIFMGWMGIYLVNRNKWGAFGDDISITIPFG

pgaudet March 2008

cDNA sequence derived from EST DDB0163023

atgttaatcccagaagatgataaactcgatgacgagaaaatgataaatatagcaaaaaaa
ctatggtttattggtttctttttcttaccatgggtttggttaattaacattttatatttt
ataccatatagaaattctttgaatgataaagtaaaatggtatttaaaattctcattaatt
ggatttttaggatattcaaccattttcatgggttggatgggtatttatttagtaaataga
aataaatggggtgcatttggtgatgatatttcaattactatcccatttggctaa

pfey July 2022

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