DDB_G0276531 - dictyBase/community-annotations GitHub Wiki

Similar to elaC, an endoribonuclease conserved from bacteria to humans, sequence variants of which are associated with aggressive prostate cancer. Nothing seems to be known about the connection between elaC and cell proliferation. The possible involvement of the Dicty gene in cell cycle control is suggested by its 3,4-fold overexpression in a Dicty strain lacking the retinoblastoma like gene rblA (Doquang et al, in preparation). Most genes associated with cell cycle progression are overexpressed in this strain.

Harry MacWilliams, April 2009


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