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Welcome to the LongSom Wiki!

LongSom: detection of somatic variants in long-read scRNA-seq data.

LongSom is a tool for detecting somatic SNVs (including mitochondrial ones, "mtSNVS"), fusions, and CNAs in high-quality (PacBio, Nanopore R10.4) long-read scRNA-seq data from cancer biopsies, and subsequently reconstructing subclonal heterogeneity, based on those variants.

Wiki contents

01. Home

02. How it works

03. Installation

04. Preparing input

05. Config file

06. Running LongSom

07. Understanding LongSom output