1. Setting up PCSX2 - antdroidx/NCAA06Next GitHub Wiki
This will be a guide to setting up PCSX2
Please obtain at least this version of pcsx2 or higher:
https://github.com/PCSX2/pcsx2/releases/
Please use v1.7.2389 or higher!
Enabling Texture Mods
In PCSX 1.7 or higher, go to Graphics Settings, and then the Advanced Tab.
Make sure to check LOAD TEXTURES at a minimum to load the texture packs.

Also, in the main Graphics settings tab, disable Mipmapping.
No interlacing/auto widescreen
https://github.com/h4wduk3n/NCAA06Next/tree/main/cheats
To use this patch, place it in your pcsx2 'cheats' folder, make sure cheats are enabled in pcsx2. In 'general' settings of pcsx2 set your display aspect to 16:9 and zoom to '0'. Finally, set deinterlacing to 'none' in GS settings. This is what worked best for me.