Does WISECONDOR ... ? - VUmcCGP/wisecondor GitHub Wiki
Check for fetal fractions?
No, I tried and I believe that the extremely low amount of reads used for WISECONDOR does not provide enough information to identify the fetal fraction reliably. I know some other methods that try to determine this fraction, but as far as I have tested them, none seem to work reliable with such low amounts of reads.
Detect aberrations on chromosome X or Y?
No, right now, WISECONDOR completely ignores non-autosomal chromosomes. Some extensions to WISECONDOR did show some promising results that might be looked into further, but for now, this is it.
Determine the fetus' gender?
No, I did come up with a method to do this but it was not merged into WISECONDOR yet. Again, WISECONDOR ignores non-autosomal chromosomes.
Do anything else?
Try this first, then ask: Simple Answers