LyxBuilder - SCons/scons GitHub Wiki
Teaching PDF to understand .lyx files
Note that this builder has been added to the SCons "contrib" repo at https://github.com/SCons/scons-contrib , as of 2016-12-07! Get your latest copy from there...
Usage
Put the tool in a findable place, such as site_scons/site_tools
.
env = Environment(tools=['default','pdftex','pdflatex','lyx'])
env.PDF(source='test.lyx')