2008 09 11 Thyroid and Regeneration John Barkhausen Ray Peat (summary)

Articles

Abbreviations

JB: past week topic: energy
JB: RP mentioned 30% brain fats regenerated?
01m50s
RP: we regenerate may be even more then 30% fats in the brain depending on the count
but complete oxidation and renewal of fats is 5% a day
example: 5% a day: https://en.wikipedia.org/wiki/Arachidonic_acid
03m15s
JB: why we regenerate fats?
RP: brains is very active metabolically
some 5% fats are oxidized, some are
some 30% fats are re-shuffled
compositions of fats are adjusted to reflect current cellular needs
05m00s
JB: regeneration takes energy?
RP: brains makes and stores https://en.wikipedia.org/wiki/Glycogen
deep sleep is needed to re-generate glycogen stores
plus you need your energy machinery working: thyroid, vitamins, minerals, etc
06m30s
JB: need to have proper foods?
RP: need to avoid https://en.wikipedia.org/wiki/Goitrogen
some vegetables, grains, nuts; other sources of pufa
avoid high concentrations of https://en.wikipedia.org/wiki/Tryptophan
avoid high concentrations of https://en.wikipedia.org/wiki/Cysteine

JB: intro for RP
08m00s
JB: explain thyroid function?
RP: https://en.wikipedia.org/wiki/Thyroid
thyroid is responsive to everything in the internal environment
more estrogen makes thyroid less responsive, and t3/t4 gets accumulated rather then released
more progesterone makes thyroid secrete more t3/t4
pufa inhibits same enzymes as estrogen
feedback example:
low t3/t4 will send more tsh to activate thyroid
but a lot of estrogen/pufa at the same time will suppress release
so thyroid will enlarge in response to tsh, yet will not release t3/t4 due to pufa
common condition in puberty/pregnancy as https://en.wikipedia.org/wiki/Goitre
so when thyroid suppression stops, it may result in burst of t3/t4 with symptoms of https://en.wikipedia.org/wiki/Hyperthyroidism
Hyperthyroidism with heart rate of 125 can mislead the doctor
so the doctor may try to kill your thyroid with https://en.wikipedia.org/wiki/Iodine-131
but in most cases this kind of Hyperthyroidism is temporary adjustment
takes few weeks to unload stored extra https://en.wikipedia.org/wiki/Thyroxine-binding_globulin
some women shared "never felt better in whole life" during this adjustment
but the doctor can kill your thyroid by misunderstanding the adjustment
11m30s
in 1950s discovered that thyroid hormone is complex: t3/t4, etc
t3 is promoter of oxidative https://en.wikipedia.org/wiki/Cellular_respiration
but it took decades for doctors to learn about it
12m15s

2008 09 11 Thyroid and Regeneration John Barkhausen Ray Peat (summary) - Ray-Peat/interview GitHub Wiki