metaP

Website

http://metap.helmholtz-muenchen.de/metap2/

Description

metaP is a web server that provides statistical analysis and pathway mapping of metabolomics data. Statistical tests provided include PCA, Mann Whitney U, Kruskal-Wallis, mean, median and standard deviation. Users can also analyse metabolite concentration ratios. Metabolites can then be mapped onto KEGG pathway maps. Data should be in the format of samples in rows and metabolite quantifications in columns. A separate file denoting experimental conditions can then be uploaded. Data gathered using Biocrates AbsoluteIDQ kits can also be directly uploaded. Users have the option to specify for the removal of outliers, noisy metabolites and reference samples from the data. If only two phenotypes are provided, metaP will additionally use the non-parametric Kendall method to test the correlation between metabolite concentrations.

Functionality

• Statistical Analysis
• Pathway Analysis

Instrument Data Type

• MS

Approaches

Computer Skills

Basic

Software Type

Web App

Interface

Web user interface

Operating System (OS)

• Unix/Linux
• Mac OS
• Windows

Language

Perl, R

Dependencies

N/A

Input Formats - Open

Metabolite quantification list in csv format

Input Formats - Proprietary

Biocrates MetIQ Output (.csv)

Published

2008

Last Updated

2010

License

Paper

https://www.ncbi.nlm.nih.gov/pubmed/20936179

PMID

20936179