crmn

Version: 0.0.20

Website

https://cran.r-project.org/web/packages/crmn/index.html

Description

Cross-contribution robust multiple standard normalization (crmn) is a CRAN package which provides normalisation for metabolomics data. crmn is a normalisation technique which can be used to normalise metabolomics data which has been generated with internal standards. A number of other normalisation methods are also included: NOMIS, One (divide each analyte by a single user-defined IS), RI (divide each analyte by the abundance estimate of the IS, closest in terms of RI), totL2 (ensures the square sum of each sample is the same), median and average normalisation.

Functionality

• Post-Processing

Instrument Data Type

• MS/GC-MS
• MS/LC-MS

Approaches

Computer Skills

Advanced

Software Type

R Package

Interface

Command line interface

Operating System (OS)

• Unix/Linux
• Mac OS
• Windows

Language

R

Dependencies

R (≥ 2.10), pcaMethods (≥ 1.56.0), Biobase, methods

Input Formats - Open

Matrix, ExpressionSet

Input Formats - Proprietary

Thermo Fisher Scientific .raw

Published

2014

Last Updated

2015

License

GPL (≥ 3)

Paper

http://www.ncbi.nlm.nih.gov/pubmed/19743813

PMID

19743813