alsace

Version: 1.14.0

Website

https://www.bioconductor.org/packages/release/bioc/html/alsace.html

Description

This bioconductor package provides tools for retention time alignment and intensity drift correction of spectra that are measured over time. It is an add on to the ALS package which implements alternating least squares (multivariate curve resolution) for analysis of chemical data, in particular hyphenated data where the first direction is a retention time axis, and the second a spectral axis e.g. HPLC-DAD (high-performance liquid chromatography with photodiode array detection). It also provides filtering of peaks below an intensity threshold.

Functionality

• Preprocessing

Instrument Data Type

• DAD/HPLC-DAD

Approaches

Computer Skills

Advanced

Software Type

R Package

Interface

Command line interface

Operating System (OS)

• Unix/Linux
• Mac OS
• Windows

Language

R

Dependencies

R (≥ 2.10), ALS, ptw (≥ 1.0.6)

Input Formats - Open

R accessible format (.csv)

Input Formats - Proprietary

N/A

Published

2014

Last Updated

2017

License

GPL (≥ 2)

Paper

PMID