MetabNet

Version: 1.0.1

Website

http://sourceforge.net/projects/metabnet/

Description

This used to map targeted MWAS data onto pathways. Full or partial correlation networks can be generated. For partial correlation analysis, the correlation between 2 variables is adjusted to take into account other variables. This is performed using the corpcor R package. For input both a peak list and a list of target metabolites with retention times must be included. For a targeted MWAS to be performed, a list of discriminatory features between conditions must also be provided. Network plots are generated and can be used as input into Cytoscape.

Functionality

• Pathway Analysis

Instrument Data Type

• MS/LC-MS

Approaches

• Metabolomics/Targeted

Computer Skills

Advanced

Software Type

• R Package

Interface

• Command line interface

Operating System (OS)

• Unix/Linux
• Mac OS
• Windows

Language

R

Dependencies

igraph, foreach, limma, rgl, doSNOW,mixOmics,WGCNA, gplots, corpcor, pcaMethods

Input Formats - Open

Peaklist, tab determined format

Input Formats - Proprietary

N/A

Published

2015

Last Updated

2017

License

GPL-2

Paper

http://www.ncbi.nlm.nih.gov/pubmed/26125020

PMID

26125020